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Curs 10-Sistemul excretor-Fiziologie renala
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Curs 10-Sistemul excretor-Fiziologie renala
Fiziologie renalaFull description...
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Fiziologia renală
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Anatomia macroscopică a rinichiului
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Anatomia macroscopică a rinichiului
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Structura nefronului
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Heterogenitatea structurală a nefronilor ~80-85% ~15-20%
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Vascularizatia renală
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Vascularizatia glomerului renal
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Vascularizatia nefronilor
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Funcţiile rinichiului Menţinerea homeostaziei organismului Eliminarea apei şi electroliţilor Detoxifiere subst. endogene (uree, ac.uric, creatinină, bilirubină, ...
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Mecanismele formării urinei
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Comportamentul substantelor substan substanttelor elor la nivel renal Filtrare
Filtrare & secreţie
X
X
Filtrare & reabsorbţie X
Filtrare & reabsorbţie totală X
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Filtrarea glomerulară
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Glomerulul renal Malpighi
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Mezangiul renal
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Reglarea umorală - SRA Aparatul juxtaglomerular
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Reglarea secreţiei de renină
Arteriola aferentă Macula
Glomerul
l a m i x o r p b u T
P -R G A 2 I
1
Na+
densa
Renina Baroreceptori
E T A
A T
1
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Sistemul renină-angiotensină
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Feed-back negativ pe secreţia de renină Angiotensinogen Arteriola aferentă Macula
Glomerul
l a m i x o r p b u T
P -R G A 2 I
1
Na+
densa
Ang I
Renina Baroreceptori
ECA E T A
A T
1
Ang II
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BRAT (Losartan)
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