BS-300 Service Manual

BS-300 Chemistry hemist ry Ana An alyz ly zer

Service Manual

© 2006 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved. For this Service Manual, the issued Date is 2006-06 (Version: 1.0).

Intellectual Property Statement tatement SHENZHEN MINDRAY MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. LTD. (hereinafter (hereina fter called Mindray) owns the intellectual property rights to this Mindray product and this manual. This manual may refer to information protected by copyrights or patents and does not convey any license under the patent rights of Mindray, nor the rights of others. Mindray does not assume any liability arising out of any infringements of patents or other rights of third parties. Mindray intends to maintain the contents of this manual as confidential information. Disclosure of the information in this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden. Release, amendment, reproduction, distribution, rent, adaption and translation of this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden. , , , trademarks or trademarks owned by Mindray in other trademarks that appear in this manual are without the intention of improperly using them. respective owners.

, are the registered China and other countries. All used only for editorial purposes They are the property of their

Respons Respons ibility ibil ity on the Manufacturer Manufacturer Party Party Contents of this manual are subject to changes without prior notice. All information contained in this manual is believed to be correct. Mindray shall not be liable for errors contained herein nor for incidental or consequential damages in connection with the furnishing, performance, or use of this manual. Mindray is responsible for safety, reliability and performance of this product only in the condition that: 





all installation operations, expansions, changes, modifications and repairs of this product are conducted by Mindray authorized personnel; the electrical installation of the relevant room complies with the applicable national and local requirements; the product is used in accordance with the instructions for use.

WARNING: It is important for the hospital or organization that employs this equipment to carry out a reasonable service/maintenance plan. Neglect of this may result in machine breakdown or injury of human health.

NOTE: This equipment is to be operated only by medical professionals trained and authorized by Mindray or Mindray-authorized distributors.

I

Warranty THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE. Exemptions Mindray's obligation or liability under this warranty does not include any transportation or other charges or liability for direct, indirect or consequential damages or delay resulting from the improper use or application of the product or the use of parts or accessories not approved by Mindray or repairs by people other than Mindray authorized personnel. This warranty shall not extend to: 





any Mindray product which has been subjected to misuse, negligence or accident; any Mindray product from which Mindray's original serial number tag or product identification markings have been altered or removed; any product of any other manufacturer.

Return Return Policy olic y Return Return Procedure In the event that it becomes necessary to return this product or part of this product to Mindray, the following procedure should be followed: 1

Obtain return authorization: Contact the Mindray Service Department and obtain a Customer Service Authorization (Mindray) number. The Mindray number must appear on the outside of the shipping container. Returned shipments will not be accepted if the Mindray number is not clearly visible. Please provide the model number, serial number, and a brief description of the reason for return.

2

Freight policy: The customer is responsible for freight charges when this product is shipped to Mindray for service (this includes customs charges).

3

Return address: Please send the part(s) or equipment to the address offered by Customer Service department

Company Contact Manufacture:

Shenzhen Mindray Bio-Medical Electronics Co., Ltd.

Ad dress dr ess::

Mindray Building, Keji 12th Road South, Hi-tech Industrial Park, Nanshan, Shenzhen, P.R.China, 518057

Phone:

+86 755 26582479 26582888

Fax:

+86 755 26582500 26582501

II

Preface Who Shoul d Read Read This Manual Manual This manual is written for service professionals authorized by Mindray.

Conventions Used Used i n This Manual Manual Safety Safety Symbols This chart explains the symbols used in this manual. When you see …

Then …

WARNING:

Read the statement following the symbol. The statement is alerting you to an operating hazard that can cause personal injury.

BIOHAZARD:

Read the statement following the symbol. The statement is alerting you to a potentially biohazardous condition.

CAUTION:

Read the statement following the symbol. The statement is alerting you to a possibility of system damage or unreliable results.

NOTE:

Read the statement following the symbol. The statement is alerting you to information that requires your attention.

Graphics All graphics, including screens and printout, are for illustration purpose only and must not be used for any other purposes.

i

Contents

Contents Preface....................................................................................................................................... Pref ace........................................................................................................................................... .... i Who Should Read This Manual .............................................................................................. i Conventions Used in This Manual .......................................................................................... i 1

Specifications....................................................................................................................1-1 1.1 1.2 1.3 1.4

2

System Feature ............................................................................................... ................................................................................................... .... 1-1 Loading System Feature .....................................................................................1-1 Analysis System Feature..................................................................................... 1-2 Others ....................................................................................... .................................................................................................................. ........................... 1-2

System Sys tem Ins tall ati on ......................................................................................... ........................................................................................................... .................. 2-1 2.1 2.2

3

System Descriptions ........................................................................................................3-1 3.1

3.2

3.3

3.4 3.5 3.6 4

Main Control Board..............................................................................................4-1 Power Drive Board ..............................................................................................4-2 A/D Conversion Board.........................................................................................4-2 Board .........................................................................................4-2 Reagent Refrigeration Board...............................................................................4-2 Level Detection Boards .......................................................................................4-3 Feeder Connection Board ...................................................................................4-3 Manipulator Connection Board............................................................................4-3 Probes Connection Board ...................................................................................4-4 Power Supply Assembly ......................................................................................4-4

Maintenance and Service.................................................................................................5-1 5.1 5.2 5.3 5.4 5.5

6

Dispensing System..............................................................................................3-1 3.1.1 Probe assemblies.................................................................................3-1 3.1.2 Disk assemblies ...................................................................................3-2 Feeder .................................................................................................................3-3 3.2.1 Feeder assemblies ...............................................................................3-3 3.2.2 Manipulator...........................................................................................3-4 Temperature Control System...............................................................................3-5 3.3.1 Temperature control assembly ............................................................. 3-5 3.3.2 Reagent preheating..............................................................................3-6 3.3.3 Reagent refrigeration............................................................................3-7 Photometric System ............................................................................................3-8 Fluid System ....................................................................................... ........................................................................................................ ................. 3-8 ISE Module (optional) ........................................................................................3-10

Funct Fun ct ions io ns of Board Bo ards s .......................................................................................... ......................................................................................................... ............... 4-1 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9

5

Check before Installation .....................................................................................2-1 Installation Procedure..........................................................................................2-1

Replacing Light Filter Assembly .......................................................................... 5-1 Replacing Optical Fiber .......................................................................................5-4 Adjusting Reaction Disk, Manipulator and Feeder .............................................. 5-7 Adjusting Probes and Disks.................................................................................5-8 Replacing Components of ISE Unit (optional)...................................................5-10 5.5.1 Replacing Tubing................................................................................5-10 5.5.2 Replacing Pumps ...............................................................................5-13 5.5.3 Replacing ISE Module........................................................................5-13

Software

Introduction.......................................................................................................6-1

1

Contents 6.1

6.2 7

System Software..................................................................................................6-1 6.1.1 System initialization..............................................................................6-1 6.1.2 Shutdown processing ...........................................................................6-2 Control Software ................................................................................................. ................................................................................................... 6-2

Servic Serv ic e Flow ......................................................................................... ...................................................................................................................... ............................. 7-1 7.1 7.2 7.3 7.4 7.5

7.6 7.7 7.8 7.9

7.10

Fluid Level Detection Failure of Reagent Probe..................................................7-1 Fluid Level Detection Failure of Sample Probe...................................................7-2 Liquid Dropping From Probes..............................................................................7-3 Failing to Detect Level of Water for Washing Exteriors.......................................7-4 Abnormal Results ........................................................................................ ................................................................................................ ........ 7-5 7.5.1 All Results Being Abnormal .................................................................. 7-5 7.5.2 Some Results Being Abnormal.............................................................7-5 7.5.3 Several Results Being Abnormal..........................................................7-6 Insufficient Light Intensity of Lamp ...................................................................... 7-7 Temperature Control Failure................................................................................7-8 Bar Code Scanner (optional) Failure...................................................................7-9 Feeder Failure .................................................................................................. .................................................................................................... 7-11 7.9.1 Transducer Distribution of the Feeder................................................ 7-11 7.9.2 Feeder Failure ....................................................................................7-12 7.9.3 Manipulator Failure.............................................................................7-13 Troubleshooting of ISE Unit (optional)...............................................................7-13

8

Mechanical Structure .......................................................................................................8-1

9

Tools and Parts .................................................................................................................9-1 9.1 9.2

10

Service Tools ....................................................................................................... ....................................................................................................... 9-1 Parts ....................................................................................................................9-1

Maintenance And Test Software....................................................................................10-1 10.1 10.2

10.3 10.4 10.5

General..............................................................................................................10-1 Command ........................................................................................ .......................................................................................................... .................. 10-3 10.2.1 Single Command Area .......................................................................10-3 10.2.2 Macroinstruction Area.......................................................................10-10 PARA and Speed Speed .............................................................................................10-13 Temperature.....................................................................................................10-19 Photoelectric....................................................................................................10-20

Ap pend ix A Board Bo ards s Co nnect nn ect io n Diagr Di agrams ams .............................................................................. A-1 Ap pend ix B Test Po ints in ts of Board Bo ards s ............................................................................................ B-1

2

Specifications

1

1.1 1.1

Specifications

System Syst em Featur Feature e 

Dimension: 980mm × 710mm × 1200mm (W × D × H)



Weight: 175kg



Power supply: AC100-130V ± 10% or 200-240V ± 10%



Input power: 1000VA



System: optional, multi-channel, multi-channel, multi-test



Scope: Clinical chemistries



Test types: end-point, kinetic and fixed-time. All support double-reagent and double-wavelength



Calibration type: Linear (single-point, two-point and multi-point), Logistic 4P, Logistic 5P, Exponential 5P, Polynominal 5P, Parabola, Spline −

1.2 1.2

X -R,



QC rules: Westgard multi-rule, Twin-plot

Cumulative sum check, Cumulative error,



Tests analyzed simultaneously: 48 (single-reagent) / 24 (double-reagent); if the ISE unit (optional) is connected, 3 (Na, K and Cl included) or 4 (Na, K, Cl and Li included) tests are added



Throughput: maximum 300tests/h; if the ISE (optional) is connected, maximum 420tests/h (Na, K and Cl included) or maximum 480 tests/h (Na, K, Cl and Li included)

Loading Loadi ng System Feature Feature 

Sample volume: 3µl~45µl; Precision: 0.5µl; for the ISE (optional), 70µl serum, 70µl plasma, 140µl diluted urine



Sample disk: general sample disk, including the inner circle and the outer circle



Sample tube position: 60 positions, including 6 calibrator positions, 3 control positions, 5 for STAT sample positions; 5 virtual disks for maximum 300 samples



Sample probe: with a built-in level detector; equipped with auto safeguard; capable of tracking sample level



Washing function: automatically washing interior and exterior of sample probe; carryover no more than 0.1%



Pre-dilution: Pre-dilution: 4 ≤ dilution rate ≤ 150, taking reaction cuvettes as the container



Reagent volume: 30-450ul; Precision: 1ul



Reagent disk: including the inner circle and the outer circle



Reagent position number: 25/50 reagent positions. Each reagent position is available for containing one Hitachi 7060 bottle, one Hitachi 7170 bottle, one Mindray inner-circle bottle or one Mindray outer-circle bottle.



Reagent probe: One independent probe which has a built-in level detector; is equipped with auto safeguard and capable of tracking reagent level



Washing Washing function: automatically washing interiors and exteriors of reagent probes; carryover no more than 0.1%

1-1 1-

Specifications



1.3 1.3

Analysis Analy sis System Feature Feature 

Lamp house: 50w lamp



Light splitting mode: Splitting by optical fiber, filtering by an interference filter.



Half band-width: 10±2nm



Wavelength: 340, 405, 450, 510, 546, 578, 630, 670, 700nm



1.4

Mixing bar: for single-reagent tests, it functions after sample dispensing; for double-reagent tests, it functions after the dispensing of the sample and the second reagent.

Absorbance range: range: -0.1~5, -0.1~5, 10mm optical optical path conversion conversion



Reaction cuvette: 5 × 6 × 25mm, optical path 5mm. Material: PP, disposable. Volume: 750uL



Reaction liquid volume: 180-500µl



Max. reaction time: 20 minutes



Reaction temperature: 37±0.3 ℃ with fluctuation of ±0.1℃

Others 

Operating system: Windows 2000 or Windows XP



Display: optional



System interface: RS-232



Printer: optional



Built-in bar code scanner: optional



ISE module: optional

1-2

System Installation

2 System Installation NOTE: The analyzer should be installed or moved to another place by Mindray-authorized personnel only.

2.1

Check before Installation The user should provide the environment that meets the requirements mentioned in the Operation Manual. Check if the environment meets the requirements before installing the analyzer. Refer to the chapter 2 of the Operation Manual for details.

2.2

Installation Procedure 1

Ensure available installation fields and environments in hospitals.

2

Confirm the reagents and calibrators.

3

Go to the installation field, and then check the delivery list for acceptance.

4

Install the four handles on the four angles of the analyzer. Move the analyzer to the installation field, fix the casters, and then remove the handles.

5

Insta ll the computer, display and printer.

6

Open the front plate, and check whether cable connections are loose. Open the top plate, check whether the probe assemblies, reagent disk and sample disk are intact and in good performance.

7

Connect the communication cable, power cable, grounding wire, waste tank and deionized water tank. Install the used-cuvette bucket, reagent probe, sample probe and mixing bar.

8

Top up the deionized water tank with deionized water.

9

Put reaction cuvettes in the feeder. Remember to check whether the surfaces of the cuvettes are smooth. In case of any bump, remove it before loading the cuvette to the compartment. Do not touch the light transmission part of the cuvette in which the colorimetric reading is taken.

10

Load acid and alkaline detergents to positions 46 and 47, and distilled water to positions 49 on the reagent disk. Load distilled water to position 60 on the sample disk.

11

Switch on the analyzer as follows: POWER → ANALYZING UNIT POWER →display → computer → printer.

12

After Windows is started, started, double-click the icon of BS-300 on the desktop to start the system software. The system program will automatically finish the self-test, become online and warm up the reaction cuvettes within about 30 minutes.

13

Select the [System/Status] System/Status] menu, and then observe the system status and record it in the table below:

2-1

System Installation Feeder Feeder status status

Unconne Unconnecte cted d

Reaction temperature

disk

Reagent temperature

disk

Full Full

Half Half full

Empty

Ambient temperature Waste tank status

Abnormal (full)

Normal (not full)

Detergent status

Abnormal (empty)

Normal (available)

Printer status

No printer

Normal

Main Main contr control ol unit unit

Unco Unconn nnect ected ed

Reac Reacti tion on disk disk unit unit

Unco Unconn nnec ecte ted d

Reag Reagen entt disk disk unit unit


Samp Sample le disk disk unit unit


Loadi Loading/ ng/unl unloa oadi ding ng unit unit

Unco Unconn nnect ected ed

Temperature unit

Unconnected

control

Idle Idle

Runni Running ng

Lamp Netw Networ ork k conn connec ecti tion on


Wavelength

Dark current

Light source base

340 405 450 510 546 578 630 670 700 Refe eferenc ence lilight sy system 14

Select the [System/Maintenance] System/Maintenance] menu. Then select the Motion Motion tab page, and implement all sub-steps of each unit to see whether they are normal. In case of any exception, adjust it.

15

Wash the interiors and exteriors of the sample probe, reagent probe and mixing bar for several times to make the fluid circuit filled.

16

Set parameters for test, reagent and calibration under theParameters theParameters menu.

2-2

System Installation 17

Request for calibration and samples, run and then debug the results.

18

After debugging the results, fill them in the table below: Test est

ALT

CREA REA

BUN BUN

Target value 2sd range Test value 1 Test value 2 Test value 3 Test value 4 Test value 5 Test value 6 Test value 7 Test value 8 Test value 9 Test value 10 19

Training Can the user complete daily tests?

Yes □

No □

Is the user familiar with the analytical methods such as kinetic, two-point, endpoint?

Yes □

No □

Is the user familiar with the daily, weekly and monthly maintenance and relevant maintenance methods?

Yes □

No □

Is the user skilled in washing dust screens?

Yes □

No □

Is the user skilled in cleaning and replacing the probes and the mixing bar?

Yes □

No □

Is the user skilled in replacing the plunger assemblies of syringes?

Yes □

No □

Is the user skilled in replacing the lamp?

Yes □

No □

Is the user skilled in maintenance of built-in bar code Yes □ scanner?

No □

Is the user skilled in maintenance of ISE unit?

Yes □

No □

Does the user know the positions, roles and Yes □ preparation methods of distilled water and acid and alkaline detergents?

No □

2-3

System Descriptions

3 System Descriptions The BS-300 analyzer consists of the analyzing unit, operation unit and output unit. The analyzing unit consists of the dispensing system, feeder, temperature control system, photometric system and fluid system.

3.1

Dispensing System The dispensing system consists of the probe assemblies (including the reagent probe assembly, sample probe assembly and mixing bar assembly), reagent disk, sample disk and reaction disk.

3.1.1 Probe assemblies Among the probe assemblies, the mixing bar assembly is the same as the reagent probe assembly and the sample probe assembly, except that the knurled axis is 30cm shorter.

Every probe assembly has a horizontal photoelectric switch and a vertical photoelectric switch. These switches are used for defining horizontal and vertical

3-1

System Descriptions initial positions of probe assemblies. The horizontal and vertical step motors precisely control the horizontal and vertical movements of the probe assemblies, and the synchronizing belts serve as the gearing. The shaft and the bushing must corporate with each other precisely, so they cannot be used confusedly.

3.1.2 Disk assemblies The three disk assemblies are different in their coders. The coder corresponds to the position where disks should stop. There is an initial-position mark under every coder. The three coders of the three disks have three coder transducers. Each transducer has two photoelectric switches for inducing the rotation and initial position of the disk.

The step motors control the disk assemblies, and the synchronizing belts serve as the gearing.

3-2

System Descriptions There is a build-in bar code scanner to the left of the sample disk. The scanner is optional.

Build-in bar code scanner

3.2

Sample probe assembly

Feeder The feeder consists of the feeder assemblies and the manipulator. It is designated to send cuvette segments to the reaction disk, take out the used ones and abandon them to the used-cuvette bucket.

3.2.1 Feeder Feeder assembl ies The feeder assemblies include the gearing assembly, cuvette compartment assembly, cuvette-pushing assembly and no-cuvette detection assembly (see the following figure). The supporting plate of the feeder assemblies is a square piece of steel that is connected to the analyzing unit by its four poles, which are secured by four nuts. Unscrewing the nuts, you can disassemble the feeder assemblies from the analyzing unit easily.

3-3

System Descriptions

There are five transducers that are shown in the figure below. The no-cuvette transducer is used to detect whether there is a cuvette segment at the loading position. The insufficient-cuvette transducer is used for determine whether there are less than 10 reaction cuvettes in the compartment or not. If yes, the analyzer will give a prompt.

Pressure Transducer

No-Cuvette Transducer

Cuvette-Pushing Limit Transducer

Insufficient-Cuvette Transducer

Cuvette-taking limit transducer

3.2.2 Manipulator Two step motors (horizontal and vertical) supply power for horizontal and vertical movements of the manipulator. The upper finger and lower finger are same in their structures. They work together to replace used cuvette segments with new ones. The manipulator runs in a relatively complicated way. There are four transducers on it: vertical transducer, transducer, horizontal transducer and two finger transducers.

3-4

System Descriptions

3.3

Temperature Control System

3.3.1 Temperature control assembly The temperature control assembly of the reaction disk consists of the temperature-controlled pot, heat-insulating sheath/plate, top heater, bottom heater, reaction disk/cuvettes, photoelectric seat, temperature transducer, fan and control circuit.

3-5

System Descriptions

1: Temperature transducer and the support 2: Fan 3: photoelectric seat 4: Heat-insulating sheath 5: top heater 6: Cover 7: temperature-controlled pot 8: bottom heater

Upper heater: square in shape, 220/110VAC, 125W Lower heater: ring in shape, 220/110VAC, 350W Total power: pow er: 475W. The function of heaters is to compensate the heat for incubating the reagent and for maintaining the temperature of the temperature-controlled chamber. Fans are used in series in the temperature-controlled chamber. It makes the air circulating in the chamber, and enhances the convective heat exchange. There are four fans in the chamber. All have the alarm function. The temperature transducer feeds back the air temperature at the position several millimeters from the bottom of the reaction cuvette. The overheat protection switch is to switch off the power when the temperature controller does work and the temperature-controlled chamber reaches 55 ℃, so as to avoid overheat or fire. When the temperature-controlled chamber becomes 35 ℃, this switch will automatically be reset.

3.3. 3.3.2 2 Reagent Reagent preheating p reheating The preheating assembly consists of two aluminum plates, a Teflon tube having nine loop sections, heating components, transducer, temperature protection switch, thermal conductive colloid, a section of tube and the reagent probe. The temperature of the thermal source of the preheater is controlled at 45 ℃. The initial temperature of the reagent is 4 ~ 10℃ 10 ℃ when it is taken out of the refrigeration refrigeration

3-6

System Descriptions chamber. When the reagent passes the heater, its temperature increases to 35 ℃. Then the reagent is added into the reaction cuvette and the preheating process is finished.

Reagent preheating assembly

3.3. 3.3.3 3 Reagent Reagent refrig r efrig eration The refrigeration module consists of refrigeration cabin, PU heat-insulating sheath, reagent disk, reagent bottle, temperature transducer, refrigeration flakes, heat sinking component, fan and control circuit. The refrigeration module is shown in the following figure.

The refrigeration assembly consists of fan, hot-end radiator, POM connector, cold-end heat-conductive aluminum block, and PELTIER refrigeration flake. Each analyzer has two such refrigeration assemblies, as shown in the figure below. The cold-side of the refrigeration flake clings to the refrigeration compartment, and the hot-side clings to the radiator (The side having letters should cling to the refrigeration refrigeration aluminum block).

3-7

System Descriptions

Each refrigeration flake corresponds to a heat-sinking block and a cooling fan. It should be installed with the cold side upward.

3.4

Photometric System The photometric system consists of a measurement photometric system and a reference photometric system. The measurement photometric system provides 9 monochromatic lights to measure the absorbance of the reacting liquid in the rotating reaction cuvettes. The reference photometric system compensates the measurement measurement photometric system to make the measurement more accurate.

Tungsten-halogen lamp Biconvex 卤钨灯聚光镜lens

Plano Main fiber convex v et e杯 tte 小透镜反u应传光束 lens C

Plano Fil光 ter片 convex 滤小透镜光电管 lens Photodiode

Fibers 传光束小端

共路

. . .

测量光路 Measurement lights

Photodiode 光电管参考光路 light Reference

3.5

Fluid System The fluid system is shown in the following figure.

3-8

System Descriptions

Sample syringe

Reagent syringe Mixing bar

As shown in the figure above, the fluid system consists of interior washing and exterior washing. The syringe assembly controls the aspiration volume by controlling the travel of the sample/reagent sample/reagent syringe. It is the core part of the fluid system.

3-9

System Descriptions

3.6 3.6

ISE ISE Module Modu le (optio (opt ional) nal) +

+

-

+

The ISE module that is used to measure the concentration of K , Na , Cl and Li in serum, plasma and urine consists of ion-selective electrodes, peristaltic pumps and calibrants.

ISE

Calibrant B Pump W

Pump A

Calibrant A

Pump B

Waste

3-10

System Descriptions

3-11

Functions of Boards

4 Functi ons of Boards The analyzer is integrated with the following boards: 

Main control board



Power drive board



Sample level detection board



Reagent level detection board



A/D conversion board



Ten photoelectric conversion boards (340nm, 405nm, 450nm, 510nm, 546nm, 578nm, 630nm, 670nm, 700nm and reference light)



Reagent refrigeration board



Power supply assembly



Manipulator connection board



Feeder connection board



Probes connection board PC Power supply assembly PFC board 12V&5V board 24V board ISE power supply board

Level detection boards Transducers

Main control board


Power drive board A/D conversion board 10 photoelectric conversion boards

4.1 4.1

Build-in sample bar code scanner

ISE module Step motors DC motors

Heaters of reaction disk

Pumps, valves

Reagent pre-heater

Lamp

Peltiers transducers

Main Main Contro l Board The main control board is the control center of the whole hardware system. It consists of the control circuits of 6 functional units (including main control unit, photoelectric unit, reagent unit, sample unit, loading/mixing unit, temperature control unit). Each functional unit has an MCU. They communicate in the multi-unit mode and thus compose the whole control system. The functions of the main control board are: 

communicating with the PC through the RS232, receiving and analyzing instructions from the PC and sending data to the PC.



controlling photoelectric conversion through the interface with the A/D conversion board, reading and saving data from the A/D conversion board.



outputting control signals of each unit through the interface with the power drive board.

4-1

Functions of Boards

4.2 4.2



receiving signals of fluid level detection and bump collision through the interface with the level detection boards.



detecting signals from temperature transducers and controlling temperature of the reaction disk and reagent preheating.



receiving signals from position transducers, deionized water transducer and waste transducer and controlling the transducers.



controlling the built-in sample bar code scanner, reading the data and sending it to the PC.



controlling the ISE module, reading the results and sending them to the PC.

Power Drive Board The main functions of the power drive board are to receive the control signals from the main control board and control drive components. The block diagram of the power drive board is shown in the figure below.

Control signals from Main Control Board

to 13 st step motors

to 2 DC DC motors

to 2 so s olenoid valves

to 3 pumps

to 2 heaters of of reaction disk

4.3 4.3

to lamp power

to 2 magnets to reagent preheating

A/D Conversi on Board The 10 photoelectric conversion circuits convert the intensity signals of the lights transmitting through the reaction cuvettes to electric signals, and then transmit them to the A/D conversion board through a 5-core shielded cable. Photoelectric conversion boards for different wavelengths have different gains and cannot be replaced by each other. The A/D conversion board filters and amplifies the 10 channels of electric signals output from the photoelectric conversion boards, transmits them through the multi-way gating switch to the A/D converter and then sends them to the main control board for further processing.

4.4 4.4

Reagent Reagent Refri Refrigeration geration Board The circuits of the reagent refrigeration board include the refrigeration circuit and the fan circuit. The refrigeration circuit is needed to work continuously, so it is powered separately. The control objects of the reagent refrigeration board include: Reagent refrigeration: 2 PELTIER components, 4 fans.

4-2

Functions of Boards Heat sink system for the whole device: 3 lamp-cooling fans, 4 temperature control fans of the reaction disk.

4.5 4.5

Level Detectio Detectio n Boards The level detection boards that include sample level detection board and reagent level detection board are used to detect the fluid level of sample and reagent separately. When the analyzer aspirates reagents/samples, the probes dip into the liquid to a specific depth, so as to avoid carryovers that have impacts on test results, and to avoid air aspiration when the reagent/sample is insufficient.

4.6 4.6

Feeder Feeder Connecti on Board The feeder connection board transfers the signals between the feeder transducer and the main control board, and connects the power drive board and the loading motor (DC). Connections:

4.7 4.7

Connector Connector

Connected Connected wit h

J91

Front transducer

J92

Back transducer

J93

Intermediate transducer

J94

No-cuvette transducer

J95

Pressure transducer

J96

Motor control wire (connected with the power drive board)

J97

Motor control wire (connected the motors)

J98

Cuvette-loading button

J99

Connection wire of the main control board

Mani Manipul pul ator Connecti on Board The manipulator connection board transfers the signals between the manipulator transducer and the main control board, and connects the power drive board and the electromagnet. Connections: Connector Connector


J101

Horizontal loading position transducer

J102

Vertical loading position transducer

J103

Electromagnet-closing transducer of the lower hand

4-3

Functions of Boards

4.8 4.8

Connector Connector


J108

Electromagnet-closing transducer of the upper hand

J104

Drive wire of the electromagnet of the upper hand

J105

Drive wire of the electromagnet of the lower hand

J106

Drive wire of the electromagnet (connected with the power drive board)

J107

Connection wire of the main control board

J109

Safeguard transducer (reserved)

J110

Safeguard transducer (reserved)

Probes Connecti on Board The probes connection board transfers the signals between the sample/reagent level detection board and the main control board, inputs the temperature signals, outputs the reagent preheating signals, and transfers the signals between the power drive board and the mixing motor (DC).

4.9 4.9

Connector Connector


J200

Interface of the sample level detection board

J201

Interface of the reagent level detection board

J202

Interface of the mixing motor (DC)

J203

Sample detection signal interface of the main control board

J204

Reagent detection signal interface of the main control board

J205

Temperature control signal interface of the reaction disk

J206

Reagent preheating signal interface

J207

Interface of the power drive board

Power Supply Suppl y Ass embly The power supply assembly consists of three boards: PFC board, 24V board, 12V&5V board and ISE (optional) power supply board. The functions of the PFC board include: 

AC/DC conversion;



Supplying the +390V and VDD voltage to the 24V board and the 12V&5V board;



Supplying stable 12V voltage for the lamp;



Supplying control signals of the analyzing unit switch to control the C12V, 5V and 24V outputs.

The 24V board converts the 390VDC current transmitted from the PFC board to the separated 24VDC outputs through the forward converter.

4-4

Functions of Boards The 12V&5V board converts the 390VDC voltage from the PFC board to B12V, C12V and 5V voltages through the forward converter. The ISE power supply board converts the 12V of the reagent refrigeration board to 24V that provides power supply for the ISE unit (optional).

4-5

Maintenance and Service

5 Main Maintenance tenance and Servi Service ce WARNING: Before disassembling or assembling the analyzing unit, ensure the POWER is placed to OFF. The probe tip is sharp and can cause puncture wounds. To prevent injury, exercise caution when working around the probe.

BIOHAZARD: Wear gloves and lab coat and, if necessary, goggles. Dispose of the waste in accordance with your local or national guidelines for biohazard waste disposal.

CAUTION: Please use Mindray-recommended consumables. Other consumables may decrease the system performance.

Refer to the BS-300 Chemistry Analyzer Operation Manual for details about

5.1 5.1



unclogging the sample probe



unclogging the reagent probe



replacing the sample probe



replacing the reagent probe



replacing the mixing bar



replacing the plunger assembly of syringe



replacing the lamp

Replacing Replacing Ligh t Filter Filter Assembly The light filter and optical assembly are fixed in the supporting sleeve. The back end is compacted and enclosed with the photoelectric amplification board and the screen gland. Generally, the supporting sleeve is replaced together with the filter and optical assembly.

5-1

Maintenance and Service Figure 5-1 Light filter assembly

Lens Screw Lens Seat Gasket Filter

Gasket

Shield Box

Photoelectric Conversion Board

Flat Spring Supporting Sleeve

WARNING: Before operating, ensure to place the POWER (main switch) to OFF.

1

Unscrew (counter clockwise) the two cap screws on the screen gland whose wavelength is to be replaced.

2

Open the cover of the A/D conversion board, and unplug the plug corresponding to certain wavelength.

5-2

Maintenance and Service 3

Take out the photoelectric conversion board and the supporting sleeve.

4

Keep the photoelectric conversion board upward, and loosen the two retaining screws on it.

5

Keep the photoelectric conversion board upward, and pull the photoelectric amplification board out of the supporting sleeve.

6

Unpack the new supporting sleeve containing the optical assembly. assembly. Be sure to keep the top side (where to assemble the photoelectric amplification board) of the supporting sleeve upward.

7

Install the original photoelectric conversion board onto the new supporting sleeve, and then fasten the two retaining screws.

8

Install the screen gland, and fasten the retaining screws.

5-3


Connect the photoelectric conversion board to the A/D conversion board, and assemble the cover.

WARNING: When replacing the light filter assembly, do not touch the optical assembly in the supporting sleeve and the photoelectric receiving tube of the photoelectric conversion board by hand. The light filters and the photoelectric conversion boards are in one-to-one relationship. Do not disarrange them.

5.2 5.2

Replaci Replacing ng Optical Fiber WARNING: Before operating, ensure to place the POWER (main switch) to OFF.

1

Unscrew the four screws on the supporting pillars of the cuvette feeder, and remove the cuvette feeder.

5-4


Unscrew the four screws on the reaction disk cover, and open the reaction disk cover. Attention should be paid to the power cable ca ble of the upper heater when wh en the reaction disk cover is being opened. Power cable of upper heater

3

Take out two cuvette segments in a diagonal with the needle-nose pliers to make two spaces for disassemble the colorimetric disk.

4

Unscrew three M3 cap screws, and then disassemble the colorimetric disk.

5-5


Use an M3 cap screwdriver to loosen the retaining screws of the optical fibers on the colorimetric clamp and the reference light support.

6

Take out the optical fibers one by one, and fix the optical components in the colorimetric clamp by fastening the screws slightly. Screw of the reference light

7

Draw out all the nine optical fibers from the reaction compartment.

8

Loosen the M3 cap screw (used for retaining optical fibers) on the lamp housing, and then draw out the optical fibers.

9

Put nine of the ten branches of the new optical fiber into the reaction disk from its bottom one by one, loosen the retaining screw, insert the optical fiber to the end, and then fasten the retaining screw.

10

Fix the reference light optical fiber.

5-6


Fix the optical fiber of the lamp housing.

12

Put the colorimetric disk back and fix it.

13

Put the reaction disk cover back and fix it.

14

Install the cuvette feeder and fix it.

CAUTION: When replacing the optical fiber, ensure that its bending radius is no less than 20cm. Otherwise, the optical fiber will be damaged.

5.3 5.3

Adj ust ing Reactio Reaction n Disk, Manip Manip ulator ulato r and Feeder Feeder NOTE: Debug the lower arm first (The relation between the lower arm position and the reaction cuvette position is very important.), and the n the upper arm. When debugging the lower arm, move the cuvette compartment aside.

1

Disassemble the cuvette feeder, and adjust the circular position of the reaction disk (through the initial position transducer of the reaction disk) to the standard position (The finger of the lower arm points to the center of the slot between reaction cuvette segments).

2

Horizontally adjust the manipulator to the standard position (The finger of the lower arm can work on reaction cuvettes well, and it should be 0.2mm away from the nearest point of the reaction cuvette).

5-7


5.4 5.4

3

Vertically adjust the manipulator the standard position (The finger of the lower arm can work on reaction cuvette well, and the finger support of the lower arm should be 0.15mm above the reaction cuvette.).

4

Run the manipulator to the position for taking new cuvettes, and horizontally adjust the reaction cuvettes in the feeder. When catching a cuvette, ensure a clearance of 0.4mm ~ 0.6mm between the finger of the upper arm and the cuvette, and center them.

Adju sting Probes and Disks NOTE: Adjust the positions of the three probes and reaction cuvettes, and then others.

1

Adjust the working position of the reagent probe (To (To minimize the cumulative error, ensure that the reagent probe return to the initial position before each adjustment.) as follows: A

For the reagent discharging position, ensure the th e reagent reagen t probe is in the center of the reaction cuvette and the probe tin is 2 ~ 3mm away from the bottom of the reaction cuvette.

B

Adjust the position of the initial-position transducer of the reagent disk. Ensure the mouths of reagent cuvettes in the inner and outer circles fit the reagent disk cover well.

C

Adjust the washing position of the reagent probe. Ensure the reagent probe is in the center of the wash well and the probe pin is 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

D

Adjust the reagent probe’s position on the outer circle of the reagent disk. Ensure the reagent probe is in the center of the hole of the outer circle.

5-8

Maintenance and Service E

2

3

4

Adjust the reagent probe’s position on the inner circle of the reagent disk. Ensure the reagent probe is in the center of the hole of the inner circle.

Adjust the working position of the sample probe (To (To minimize the cumulative error, ensure that the sample probe return to the initial position before each adjustment.) as follows: A

For the sample discharging position, ensure the sample probe is in the center of the reaction cuvette and the probe tin is 2 ~ 3mm away from the bottom of the reaction cuvette.

B

Adjust the position of the initial-position transducer of the sample disk. Ensure the mouths of sample cuvettes in the inner and outer circles fit the reagent disk cover well.

C

Adjust the washing position of the sample probe. Ensure the sample probe is in the center of the wash well and the probe pin is 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

D

Adjust the sample probe’s position on the outer circle of the sample disk. Ensure the sample probe is in the center of the hole of the outer circle.

E

Adjust the sample probe’s position on the inner circle of the sample disk. Ensure the sample probe is in the center of the hole of the inner circle.

Adjust the working position of the mixing bar. A

Switch off the analyzing unit first, and then rotate the mixing arm ar m to see if its rotation radius is proper. If the mixing bar cannot reach the center of the reaction cuvette, adjust the position of the mixing bar on the mixing arm properly.

B

Disassemble the mixing arm, and then switch on the analyzing unit to run the reaction disk and stop it at any cuvette. Hold the mixing arm by hand, and fix it at the center of the reaction cuvette.

C

Vertically adjust the mixing bar’s position in the reaction cuvette. Ensure the mixing bar tip is 1 ~ 2mm away from the bottom of the reaction cuvette.

D

Adjust the washing position of the mixing bar. Ensure the mixing bar is in the center of the wash well and about 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

In the engineering adjustment software, select the Debug instruction menu, and rotate the reaction disk for one lap. Dive probes and mix the reactant at every position or every several positions to see if the three probes interfere with any reaction cuvette (Command 61). If the mixing bar knocks the side or the bottom of any cuvette, repeat Step 3.

5-9


5.5 5.5

Repl Replacing acing Components Compo nents of ISE ISE Unit (opti onal)

5.5.1 5.5.1 Replaci Replaci ng Tub Tubing ing NOTE: (1) Fluidic tubing can be divided into the following six types. W1 with two adapters connects the ISE module and the pump W. Pump module

ISE module

Reagent module to be placed here

Pump tubing adapter Pump tubing Pump head

Pump B

Pump A

Pump W

Fluidic tubing adapter

W2 connects the reagent module and the pump W. A1 (B1) with one adapter connects the sample entry port and the pump A (pump B). A2 (B2) with two adapters connects reagent module and the pump A (pump B). They are different in length and W1, A2 and B2 are not directional when they are installed. Usually the adapter has not been mounted to the fluidic tubing, so you have to do it by hand. The tubing should be mounted to a short metallic tube on the adapter. For convenience, the connecting end of the tubing can be dipped into hot water for several seconds. (2) Pump tubing is used around a pump head. It has one adapter on each end that makes connection with the fluidic tubing easy.

5-10


5.5.1. 5.5.1.1 1 Replacin g Fluid ic Tubi Tubi ng W1 and W2 1

Place the POWER to OFF. OFF.

2

Open the ISE unit door.

3

If you want to replace the W1, unscrew the screw of the ISE module and take off the cover.

4

Put out the fluidic tubing W2 and insert it into a container such as a cup that is used to contain the waste solution flowing from the W2.

5

Start the analyzing unit and the system software.

6

Enter the ISE Maintenance screen Maintenance screen of the system software.

7

Click the Maintenance Maintenance button several times until there is no solution flowing out from the W2.

8


9

If you want to replace W1, pull out its two adapters directly from the waste pump tubing adapter and the right angle adapter that is fixed to the compression plate. Right angle adapter

The side matches the adapter of fluid tubing W1 The side with a recess matches the compression plate of the ISE module.

Note that when pulling out the fluidic tubing adapter, in order not to release the right angle adapter, you can hold the right angle adapter with a finger. After that, install a new W1. For W2 exchange, it just needs to replace the W2 with a new one. 10

If you want to replace the W2, replace it with a new new one. Otherwise, insert the W2 back to the reagent module.

11

Place the POWER to ON.

12

Enter the System Maintenance screen Maintenance screen of the system software.

13

Select the Others tab Others tab and click the Download Settings button. Settings button.

14

Enter the ISE Maintenance screen. Maintenance screen.

15

Click the A the A p urge ur ge button button to observe if there is solution leaking out. If there is solution leaking out, repeat from the step 4 to install the tubing again.

16

Install the cover of the ISE module if it has been taken off.

17

Close the ISE unit door.

5-11


5.5.1. 5.5.1.2 2 Replacin g Fluid ic Tubi Tubi ng A1, A2, B1 and and B2 1


2

Take off the panel under the sample disk and you can see the shielding box and the peristaltic pumps.

3


4

Take out the reagent module.

5

Put the fluidic tubing W2 in a container such as a cup that is used to contain the fluid flowing out from the W2.

6

Start Start the analyzing unit and the system software.

7


8

If you want to replace A1 or A2, click the A the A purg pu rge e button. If you want to replace B1 or B2, click the B purge button. purge button. Repeat this step for several times until the received data indicates that the Calibrant A or Calibrant B has air bubble in it.

9


10

Replace the tubing with a new one. Note that before installing the A1 or B1 to the sample entry port, you can dip the connecting end of the A1 or B1 into hot water for several minutes to make the following procedures easily performed.

11

Start the analyzing unit.

12

If the system software is not running, start it. Otherwise, enter theSystem the System Maintenance Maintenance screen of the system software, select the Others Others tab and click the Download Settings button. Settings button.

13


14

If you have replaced A1 or A2, click the A the A purg pu rge e button. If you have replaced B1 or B2, click the B purge button. purge button. Repeat this step for several times until the received data indicates that the Calibrant A or Calibrant B has no air bubble in it.

5.5.1. 5.5.1.3 3 Replacin g Pump Tubi ng 1


2


3

Pinch one adapter of the pump tubing and take it out from the tubing shelf. Then take off the whole tubing.

Tubing shelf

5-12


Put one adapter of the new pump tubing onto the tubing shelf and make the tubing around the pump ahead, then put the other adapter onto the shelf with a little strength.

5


6


7

Click the Pumps button Pumps button to see if the calibration of pump is correct. If not, repeat the upper steps.

5.5.2 5.5.2 Repl Replacing acing Pumps 1


2

Take off the pump tubing around the pump head.

3

Disconnect the cable and the pump motor.

Cable

Pump motor

4

Unscrew the four screws around the pump head.

5

Pull out the pump directly. directly.

6

Put a new pump on the pump shelf, tighten the screws, connect the calbe and pump motor, and then put the pump tubing around the pump head.

7


8


9

Click the Pumps button Pumps button to see if the calibration of pump is correct. If not, repeat the upper steps.

5.5.3 Replacing ISE Module Some times there is something wrong with the components in the ISE module such as sample entry port, bubble detector, PCB and so on. In these cases, the ISE module should be replaced according to the following procedure. 1


2

Take off the panel under the sample disk and you can see the shielding box and the pumps easily. easily.

3


4


5

Enter the ISE the ISE Maintenance screen. Maintenance screen.

5-13


Click the Maintenance button. Maintenance button.

7


8

Unscrew the screw of the ISE module and take off the cover.

9

Take off all electrodes from above to below.

10

Disconnect the right angle adapter and the compression plate.

11

Disconnect the cable.

12

Unscrew the four screws that fix the ISE module to the shielding box. Then take out the module from the shielding box.

13

Put a new ISE module to the shielding box. Then connect the cable and install the electrodes sequentially. At last mount the right angle adapter to the compression plate.

14

Install the electrodes sequentially.

15

Enter the System Maintenance screen Maintenance screen of the system software.

16

Select the Others tab Others tab and click the Download Settings button.

17

Enter the ISE the ISE Maintenance screen. Maintenance screen.

18

Click the A the A purg pu rge e button to see if there is solution leaking out. If there is, take off the electrodes and install them again.

19

Check if the new ISE module can work normally. normally.

5-14

Software Introduction

6 Software Introduction The software of BS-300 analyzer is composed of the system software and the control software.

6.1 6.1

System Syst em Software Softw are The system software can, according to the requirements and inputs of users, generate a work schedule (instruction sequence), control the units of analyzing unit in the sequence of instructions in the work schedule, receive photoelectric data, response messages or execution results from the analyzing unit, output them to the PC screen or the printer. printer. With these outputs, users can obtain correct test results. According to different different functions, functions, the entire PC software system can be divided divided into the following parts: 

System Initialization

This part includes the initialization of the PC operating system, the initialization of the communication communication between the PC and analyzing unit, and the controls of analyzing unit reset. 

Control system

This part includes the formation of the work schedule, instruction data sending and receiving. 

GUI

This part includes the requests for tests (routine tests, emergency tests, calibration tests and QC tests), the observation of test status (status of the reaction disk, sample disk and reagent disk), test management, calibration management, QC management, result query, alarm management and the help system. 

Shutdown Processing

This part includes the resets of sub-units.

6.1.1 System initialization To initialize the PC operating system, 

Check the PC operating system. The system software must run under Windows 2000 or Windows XP. Otherwise, the system will prompt that the system software cannot run under other operating system, and then the system software system exits automatically.



Check the current screen resolution for the operating system. The system software must run under the resolution of 1024 × 768. Otherwise, the system prompts to reset the resolution before restarting the system software and exit the system software.



Disable the screen protection program. The system software must keep displayed while running. To prevent the screen protection program from disturbing users in the operating and observing processes, disable it.



Lock the keyboard. When running, the system software will lock some key combinations to prevent users from starting any other program and conducting any

6-1

Software Introduction other operation. In this case, users cannot switch over to any other program or print the current screen. 

Check whether there is any username and password of the maintenance/debugging personnel in the registry. The system software has the debugging function. Only the authorized maintenance/debugging personnel can enter the debugging window and maintain or debug the system and the host. For the confidentiality, the username and password are saved in the registry. If they are unavailable in the registry, the system will re-write the default username and password into the registry.

To initialize the communication and the units auto-check, 

Set serial ports and initialize them, including such parameters as the baud rate, data bit, start bit, stop bit, parity bit, transmitting/receiving buffer, control protocol and so on. In addition, start the serial port receiving thread.



Handshake for communication. Send a handshake instruction to t he analyzing unit. If the analyzing unit responds to this instruction (namely, send back a handshake instruction to the PC), it indicates the PC handshakes handshakes with the host successfully. successfully. If the host fails to respond to handshake instruction, it will re-send the handshake instruction back in a specific period. If it fails for continuously three times, the system will prompt to exit the system software. If you ignore that and continue to enter the system software, all tests cannot be conducted under the system.



Check whether the printer is connected. If not, the system will prompt to connect it.



Send an instruction for querying the auto-check results of the units, check the auto-check result of each unit. (The units are auto-checked when the analyzing unit is started, and the auto-check results are stored in the main unit.) In case of any fault data in the auto-check result of any unit, the system will prompt to switch off the analyzing unit and check the faulty unit.

6.1. 6.1.2 2 Shutdown pr ocessin g In the BS-300 Chemistry Analyzer Control System window, click the Exit button. Exit button. The Confirm dialog Confirm dialog box appears. If you click OK, OK , the system will

6.2 6.2



Switch off the lamp;



Unload all reaction cuvettes;



Wash the fluid tubing;



Reset all units;



Unlock the keyboard;



Prompt to exit the operating system and shut down the PC.

Contro l Software The analyzing unit can be functionally divided into the following units: photoelectric unit, reaction disk unit, reagent disk unit, sample disk unit, reagent probe syringe unit, sample probe syringe unit, mixing bar unit, loading and manipulator unit, temperature control unit, fluid tubing unit and reagent refrigeration unit. The functions of those units are listed in the following table.

6-2

Software Introduction Unit

Function

Main unit

Receives macroinstructions macroinstructions from the PC, decomposes decomposes them into a series of action instructions, and then delivers the action instructions to destination sub-units sub-units (in specific order) at a certain interval. Monitors the status of other units, and transmits data collected by the photoelectric unit to the PC.

Photoelectric unit

Photoelectrically Photoelectrically detects, amplifies and converts the solution in reaction cuvettes, and stores A/D converted data at the twin port FIFO for the main unit to read and transmit them to the PC.

Reaction unit

disk

Contains 80 cuvette No.

Reagent unit

disk

Sample unit

disk

Runs the reaction cuvette with the specified No., following the instruction of the main unit, to the reagent dispensing position, sample dispensing position, mixing position, and photoelectric detection position at all wavelengths. Contains 50 bottle positions. Carries reagents, and runs the reagent bottles with specified No., following the instruction of the main unit, to the reagent aspirating position. Contains 60 tube positions in the inner and outer circles. Carries samples, and runs the sample tubes with specified No., following the instruction of the main unit, to the sample aspirating position.

Reagent probe syringe unit

Receives instructions from the PC, and controls the reagent probe in aspirating a specific volume of reagent from the reagent bottle and dispensing it to the specified reaction cuvette.

Sample probe syringe unit

Receives instructions from the PC, and controls the sample probe in aspirating a specific volume of sample from the sample tube and dispensing it to the specified cuvette.

Mixing bar unit

Receives instructions from the PC, and controls controls the mixing mixing bar in mixing the solution in the cuvette that has been run to the mixing position. Runs the mixing bar to the wash well, and wash it after each mixing process to avoid carryover.

Loading and manipulator unit

Controls the cuvette feeder and manipulator. The feeder assembly is responsible for detecting whether there are enough reaction cuvettes in the cuvettes compartment and pushing reaction cuvettes to the position for the manipulator to take cuvettes. The manipulator is responsible for taking reaction cuvettes from the reaction disk, placing them into the used cuvette bucket, taking new reaction cuvettes from the cuvette compartment, compartment, and putting them on the reaction disk.

6-3

Software Introduction Unit Temperature control unit

Function Controls the reaction disk temperature, reagent probe preheating temperature and fluid tubing. Note: Note: The reaction reaction disk temp temperat erature ure should should be be kept kept at 37 37 ℃, the heating cavity of the reagent probe should be preheated to 45 ℃.

Fluid tubing unit

Controls the t he fluid tubing tubi ng in washing the t he reagent probe, sample probe and mixing bar.

Reagent refrigeration unit

Refrigerates the reagent chamber temp temper erat atur ure e bet betwe ween en 4 ~ 10 10 ℃.

6-4

and

controls

its

Service Flow

7 Service Flow WARNING: Before disassembling or assembling the analyzing unit, ensure the POWER is placed to OFF. The probe tip is sharp and can cause puncture wounds. To prevent injury, exercise caution when working around the probe. When you disassemble or replace any board, ensure to wear antistatic gloves.

BIOHAZARD: Wear gloves and lab coat and, if necessary, goggles.

7.1 7.1

Fluid Level Level Detectio Detectio n Fail Failure ure of Rea Reagent gent Probe Surface detection signal transmission error: The surface detection board does not have the working voltage, or when the probe touches the surface, the indicator of the surface detection board is normal, but there is always a host alarm indicating surface detection failure. Possible cause: The patch cord for the reagent surface detection is disconnected, or the connector is not well connected.

The reagent probe cannot detect the surface on the reagent disk

Surface detection failure of reagent probe(Th e reagent probe does not detect the surface on the reaction disk.)

Surface detection signal processing error: When the probe touches the surface, the indicator of the surface detection board is normal, the connection between the main control board and the surface detection board is normal, and no surface detection signal reaches the main control board, but there is always a host alarm indicating surface detection failure. Possible cause: Main control board. board. Power failure: The working voltage of the surface detection board is 12V. In case of no power supply, the surface detection signal cannot be generated. Possible cause: Disconnection; the connector is not well connected; there is no 12V output from the main control board. Probe failure: The detection terminal has a changeable capacitance. Loose exterior or interior of the probe, the sealing-off of the probe connecting wire and the probe breakage will result in unsteady voltage or obvious voltage changes. In this case, the capacitance signal will be unavailable or exceed the range of the surface detection board. Possible cause: Reagent probe assembly, connector.

The surface detection signal fails to be generated by capacitance change.

Surface detection board failure: When there is no probe failure, but the indicator is always on, or the indicator is not on when the probe touches the surface, there must be a surface detection board failure. Troubleshooting: Replace the surface detection board.

The reagent probe misdetected the surface

When this failure occurs, the sample probe cannot detect the surface at the reaction disk, but there is no alarm at the reagent unit. For details, see Surface Detection Failure: Sample Probe.

7-1

Service Flow

7.2 7.2

Fluid Level Level Detectio Detectio n Fail Failure ure of Sampl Sampl e Probe

The sample probe cannot detect the surface at the reaction disk.

No reagent in the reaction disk: The reagent probe misdetects the surface, aspirates air and dispenses into the reaction cuvette. Therefore, the reagent unit CPU fails to make any judgment. In this case, the sample probe cannot detect the surface when dispensing the sample into this reaction cuvette. Possible cause: Surface detection failure of the reagent probe insufficient reagent: The reagent probe aspirates less reagent than the set volume. As a result, the sample probe cannot detect the surface at the preset height. Possible cause: The reagent is prepared in the bottle, the reagent syringe is not fixed, leakage occurs in the tubing of the reagent probe, or there are bubbles in the reagent. Position correction parameter error of the sample probe: In case of such an error, the sample probe cannot reach the surface in the steps. Troubleshooting: Re-correct the sample probe position. Surface detection signal transmission failure: When the probe touches the surface and stops, the indicator of the surface detection board is on for about 2 seconds. The output signal of the surface detection board switches normally, but there is always a host alarm indicating that no surface is detected. Possible cause: The patch cord for detecting the sample surface is disconnected, or the connector is not well connected.

Surface detection failure of the sample probe

The sample probe cannot detect the surface at the reaction disk.

The sample probe misdetects the surface (In this case, there will be no alarm, but test results will become abnormal. On the reaction curve, you can see that no sample is added.)

Signal processing failure of the main control board: When the probe touches the surface, the indicator works normally. But there is always a host alarm indicating that no surface is detected. Ensure that the sample surface detection signal is transmitted to the relevant connector of the main control board. Possible cause: Main control board failure Surface detection signal failure: The indicator of the surface detection board is not on or always on when the sample probe touches the surface. Surface mis-detection at the sample disk: In this case, there will be no alarm, but the sample probe fails to aspirate the sample, and the test result and reaction curve become abnormal. Possible cause: Sample probe, surface detection board, surface detection patch cord. Surface mis-detection at the reaction disk: In this case, there will be no alarm, but there is residual sample on the sample probe tip, and drops on the table when the probe leaves the reaction disk. Possible cause: The sub-unit software is later than V1.7, or the sample probe is not in the center of the reaction cuvette.

7-2

Service Flow

7.3 7.3

Liqu id Dropping From Probes Probes Drips drop from the sample probe due to fluid tubing leakage. In this case, there will be liquid dropping onto the table widely, and there may be liquid dropping even when the sample probe is static.

Troubleshootin g for the liquid dropping from the reagent probe and sample probe. Drips drop from the sample probe due to surface detection failures. In this case, most liquid drop on the area between the reaction disk and the wash well.

Tubing leakage due to the abraded syringe piston Troubleshooting: Replace the syringe or the syringe piston

The reagent probe takes liquid from the reaction disk. The reagent probe did not detect the surface at the reaction disk, and dispenses the reagent at the corresponding height. If the reagent probe cannot touch the surface at the position for dispensing reagent, the last reagent drop will be taken out by the reagent probe. Possible cause: The probe arm is installed at a too high position; the position of the sample probe has not been corrected; the syringe is loose; there are bubbles in the reagent bottle.

The sample probe takes liquid from th e reaction disk. The sample probe detects the surface and stops immediately. Then it dispenses the sample at 1mm under the surface. If the reagent probe mis-detects the surface, the dispensed sample will fail to be added into the reagent, but taken at the probe tip and drops when the probe is moving. As a result, some test results become abnormal. Possible cause: There are bubbles in the reaction cuvette; the sample probe is not in the center of the reaction cuvette, and its position has not been corrected.

Drips taken from the reagent disk or sample disk and dropping from probes Such failures are usually followed by alarms indicating that no surface is detected at the reagent/sample disk. The reagent/sample probe does not aspirate reagent/sample, but the reagent/sample probe will stretch out to the bottom of the reagent bottle/sample tube due to surface detection failures. As a result, reagent/ sample liquid will be taken on the exterior of the probe and drop while the probe is moving.

Probe being bent Troubleshooting: Replace the probe.

Smudges on the sample probe absorb some liquid and drop it while the probe is moving. Troubleshooting: Cleaning the sample probe. Other failures Probe driving assemblies are not assembled well, resulting in probe jittering and liquid dropping in the vertical movements. Troubleshooting: Adjust or replace the probe driving assemblies.

7-3

Service Flow

7.4 7.4

Faili Faili ng to Detect Detect Level of Wate Waterr for Washin Washing g Exteriors Surface detection signal failure: See relevant resolutions for the surface detection failure.

No water in the wash water tank: Users can see this failure in the alarm information detergent empty . In case of no alarm information, check whether there is any problem in the detergent tank cover assembly.

Failing to Detect the Surface of the Water for Washing Exteriors

Pump damaged: In this case, there will be no water in the three wash wells. Troubleshooting: Replace the pump. No water in the wash well Tubing blocked: In this case, there will be insufficient water for washing exteriors, the three water flows are not the same, or there will be no water in any of the three wash wells. Possible cause: The unidirectional valve is blocked, or the detergent entrance is blocked.

The tube is disconnected. Possible cause: The tube is degraded, or other causes. Troubleshooting: Connect the tubes again.

Reagent or sample probe. Solution: Replace a probe

7-4

Service Flow

7.5 7.5

Abn orm al Resul Resul ts

7.5. 7.5.1 1 A ll Results Being Abn ormal No sample or insufficient sample is added. In this case, it can be seen on the reaction curve that the absorbance has not increased in the period for adding the sample. The reaction curve is even, and many results are 0. Possible cause: Sample probe blocked, tubing leakage, syringe not fixed, valve not shut tightly.

All results are lower than normal results.

The reaction is not thorough. If the sample is not mixed uniformly with the reagent, the reaction will not be thorough, and the light cannot detect the changes of the absorbance. Possible cause: The mixing bar did not mix the reacting liquid.

All test results are abnormal

Some results are higher, and some are lower, with bad repeatability.

The volumes of dispensed sample are not the same. In this case, it can be seen from the reaction curve that the response is proportional to the volume of the sample. Possible cause: Tubing leakage, valve not shut tightly, or cuvette segments not cleaned well.

7.5.2 Some Results Being Abnormal Good repeatability Troubleshooting: Re-calibrate it.

Bad repeatability Observe the reaction curve, and find the possible causes. Some test results are abnormal. All test results are approaching approaching to 0. 0. Observe the reaction curve first. Possible cause: The lamp base of corresponding wavelength exceeds 65535; the photoelectric detection unit fails to detect the change of absorbance, reagent failure and optical fiber disconnection.

7-5

Service Flow

7.5.3 Several Results Being Abnormal Several test results are too low. In this case, observe the reaction curve first. Possible cause: Drips dropping from the sample probe Several test results are abnormal

Several test results suddenly become too high. In this case, observe the reaction curve first. Possible cause: There are bubbles in the current cuvette; the mixing bar knocks the cuvettes.

7-6

Service Flow

7.6 7.6

Insufficient Ligh t Intensity of Lamp Insufficient Light Intensity of the Lamp

Record the lamp background value and gain

Measure and record the lamp background value and gain

Lamp background values of all channels decreases.

Lamp base values of several channels decreases

Replace lamb

Estimate whether the lamp has worked for 2000h (lifetime), replace Lamb

S E Y

Replace the lamp. Check whether the AD value of the channel whose lamp vase value is smaller increases obviously.

YES

O N

Replace the lamp with the original lamp

Adjust the gain gain parameter to make make the lamp base AD values of all channel lamps increase to about 62000.

Replace the photoelectric transducer assembly, and then check whether the lamp base value increases obviously. YES

Replace the photoelectric transducer assembly.

Remove the fault alarm

Replace the optical fiber

Clean the photometric system (such as the lens)

NO

YES

Change the positions with the smaller fiber end, and check whether the lamp base value increases obviously. O N

YES

Check whether the photometric system (such as the lens) corresponding corresponding to the fiber channel is covered with dirt or the like. (If yes, clean it.) Then check whether the lamp base value increases obviously

Note: Do not adjust the photoelectric gain parameter in case you have no idea about the cause for the alarm indicating insufficient light intensity of the lamp.

7-7

Service Flow

7.7 7.7

Temperatu re Contro Cont roll Fail Failur ure e Temperature control failure

Query and record the fault log codes and descriptions.

Monitor the temperature curve.

Obtain the current temperature control parameter, and check whether it is the same as the factory parameter.

Replace the temperature transducer.

Enable and disable the temperature control function repeatedly for 2 ~ 3 times

NO

Check whether the temperature transducer is normal.

s e y

Replace the heating assembly.

NO NO

Check whether the heating resistance is normal.

S E Y

Restart the analyzer and then check whether it is normal.

1

To monitor the temperature curve A

In the BS-300 Chemistry Analyzer Control System window, select the [System/Temperature [System/Temperature]] menu. A dialog box appears. Enter BS300DEBUG BS300DEBUG and MINDRAY MINDRAY respectively in the User Name Name and Password Password text boxes. Then click OK OK to enter the Temperature Control Curve window. Curve window.

B

Set a proper temperature range for observing the change of the temperature curve, and then click the Start button. Start button.

7-8

Service Flow

2

3

C

Minimize the Temperature Control Curve Curve window for future observation at any time.

D

After that, print or snap the temperature curve and then return it to the headquarters together with the service work report.

To measure the impedance of the temperature transducer A

Switch off the BS-300 analyzer.

B

Open the left side plate of the BS-300 analyzing unit to expose the main control board.

C

Unplug J45 (reagent preheating temperature transducer), and measure the resistance between PIN1 and PIN3 with a multimeter. The relation between the resistance and the temperature is: 25℃ /1100Ω, 38.5℃/1145Ω, 45℃/1170Ω, 50℃/1170Ω.

D

Unplug J44 (reaction disk temperature transducer), and measure the resistance between PIN1 and PIN3 with a multimeter. The relation between the resistance and the temperature is: 25℃/1100Ω, 38.5℃ /1145Ω, 45℃/1170Ω, 50℃/1170Ω.

To measure the resistance of the heater A

Measure the impedance of the reagent preheater in the following procedures: Unplug J24 (power driving board) Measure the impedance between PIN1 and PIN2. Reagent preheater (BA30-10-06626)/24.6 to 28.5Ω.

B

Measure the impedances of the upper and lower heaters of the reaction disk in the following procedures: Disconnect the connecting wire from J113 of the power patching board. Measure the impedances of the upper and lower heater: upper temperature-sensitive heater (BA30-10-06624)/437.8 to 483.8Ω, lower temperature-sensitive heater (BA30-10-06625)/131.4 to 145.2Ω.

7.8 7.8

Bar Code Scanner Scanner (optio nal) Failu Failu re WARNING: Light sent by the bar code scanner may hurt your eyes. Do not stare into the laser beam from the bar code scanner.

If the bar code scanner cannot emit laser, you can service it according to the following steps. 1

Place sample tubes with bar code labels that meet the requirements mentioned in the operation manual.

2

Restart the analyzer.

7-9

Service Flow 3

Enter the Scanner Setup Setup & Maintenance screen Maintenance screen of the system software.

4

Enter the Maintenance tab. Maintenance tab.

5

Enter the sample position range in the Sample Position field Position field and click the Step Scan button. Scan button. Observe if the scanner can emit laser. If not, click the Laser on button. on button. If the scanner still cannot emit laser, go to the next step.

If the bar code scanner emits laser normally but is failed in reading, you can service it according to the following steps. 1

Place the ANALYZING UNIT POWER to OFF. OFF.

2

Place sample tubes with bar code labels that meet the requirements mentioned in the operation manual.

3

See if the window on the sample department is stained. If so, clean the window with absolute alcohol-dipped gauze and go to the next step. If not, go to the step 8.

4

Restart the analyzer.

5

Enter the Scanner the Scanner Setup Setup & Maintenance screen Maintenance screen of the system software.

6


7

Enter the sample position range in the Sample Position field Position field and click the Step Scan button. Scan button. Observe the scanning procedures to see if the scanner can read the bar codes. If not, go to the next step.

8

Enter the Setup tab. Setup tab.

9

Select all symbologies but do not select any Check or Check or Length. Length .

10


11

Click the Scan button Scan button to see if the scanner can read the bar codes. If not, go to the next step.

12

Place the test fixture to the position 28 on the sample disk.

13

Click the Mechanism button Mechanism button at the System Maintenance screen Maintenance screen to reset all mechanical parts. If the laser from the scanner cannot reach the bar code through the slit on the test fixture, adjust the screws on the brackets until the laser from the scanner can reach the bar code.

7-10

Service Flow

Bracket 1

Bracket 2

14

7.9

If the scanner cannot read the bar codes successfully, replace the bar code scanner. If the new scanner cannot read the bar code, you need to check the bar code labels the user used.

Feeder Feeder Failu re

7.9. 7.9.1 1 Transd Transd ucer Distr ibut ion of the Feede Feederr Pressure Transducer

No-Cuvette Transducer

Cuvette-Pushing Limit Transducer

Insufficient-Cuvette Transducer

7-11

Cuvette-taking limit transducer

Service Flow

7.9.2 Feeder Failure

The trolley moves backward to the end, but does not move forward. Possible causes:

Feeder failure symptom

1. The cuvette-taking limit signal has not been detected. 2. The belt is too tight, so the motor cannot run. Troubleshooting: 1. Check whether the voltage is 0 when the cuvette-taking limit optical coupler is blocked. 2. Adjust the position of the motor to loosen the belt.

The trolley moves forward and stops before compacting the cuvette segment

1. The moving resistance is too large, so the trolley fails to compact the cuvette segment, but the pressure transducer has been blocked. 2. The sliding block falls off, resulting in large friction. 3. The motor cannot work normally. 4. The belt is too tight. Troubleshooting: 1. Clean the guiding axis of the trolley. 2. Replace the sliding block assembly. 3. Replace the motor. 4. Loosen the belt.

The trolley keeps moving backward and forward

1. The no-cuvette transducer has not been pressed completely, so the system deems that the cuvette compartment is empty, and the trolley moves back for cuvette segments. Troubleshooting: 1. Adjust the position of the no-cuvette transducer. 2. Replace the feeder assemblies.

7-12

Service Flow

7.9.3 Manipulator Failure

Manipulator verticalmovement error: Cannot reach/leave the initial position.

The signal of the vertical optical coupler has not been detected after the motor runs for specified steps. Possible causes: 1. The resistance of the lead screw is too large (frequently). 2. The optical couplers for the vertical initial position cannot work (scarcely). 3. The vertical motor of the manipulator cannot work (scarcely). 4. The optical coupler connector is not connected well (infrequently). 5. The power driving board cannot work (infrequently). 6. The main control board cannot work (scarcely).

Troubleshooting: 1. Lubricate the lead screw after cleaning it. 2. Replace relevant assemblies.

The upper hand of the manipulator cannot close/open. Direct cause: The finger signal has not been detected after the electromagnet of the manipulator is switched on.

1. The snap ring of the manipulator is not flexible (infrequently). 2. The coupler of the upper finger cannot work any more (scarcely). 3. The upper hand of the manipulator is not arranged well with the position of the feeder/reaction disk (frequently). 4. The coupler connector is not connected well (infrequently).

1. Adjust the positions of the upper hand and the feeder/ reaction disk. 2. Replace the manipulator (Its position must be adjusted).

1. The operator has added too many cuvette segments into the feeder (behind the trolley). When the trolley moves backward, the jaw is pressed back by the cuvette segments; when it moves forward again, the hand fails to open in time, so the jaw may press one side of the trolley only. As a result, the cuvette segment at the front fails to corporate with the upper hand of the manipulator well (frequently). 2. The lower hand of the manipulator fails to corporate with the reaction disk position well (frequently). 3. The snap ring of the manipulator is not flexible (infrequently). 4. The lower hand coupler of the manipulator cannot work any more (scarcely).

1. Press the cuvette-taking key after adding cuvette segments into the feeder. 2. Adjust the positions of the lower hand and reaction disk. 3. Replace the manipulator (Its position must be adjusted)

1. The snap ring of the manipulator is not flexible (frequently). 2. The finger coupler of the manipulator cannot work any more (scarcely).

Troubleshooting: 1. Replace the manipulator (Its position must be adjusted).

Manipulator Failure

The lower hand of the manipulator cannot close/open. Direct cause: The finger signal has not been detected after the electromagnet of the manipulator is switched on.

The upper/lower hand of the manipulator accidentally closes/ opens. Direct cause: After the manipulator is switched on, the finger coupler signal is received, but the signal changes suddenly while the manipulator is moving.

7.10 7.10 Trou bleshoot bl eshoot ing o f ISE ISE Unit (optio nal) When there is something wrong with the ISE unit, an error code will be displayed at the screen and saved in the log. The error code of the ISE unit has a format of 7 ASCII characters, the format of which is <1234567>. Each digit represents a certain error. 

Digit 1: Air in sample, Calibrant A, Calibrant B, Bubble Detector, mV range.



Digit 2: Sample/Calibrant B mV range.

7-13

Service Flow 

Digit 3: mV out of range for Calibrant A in Sample Cycle, or Calibrant B in Urine Cycle.



Digit 4: Noise in mV of Calibrant B in Calibration Cycle, or Sample mV during a Sample Cycle.



Digit 5: mV Noise in Calibrant A of the Calibration Cycle, or Sample Cycle, mV Noise in Calibrant B of the Urine Cycle.



Digit 6: mV Drift of calibrant A.



Digit 7: Slope of Sample value is out of range.

Each row represents where the error locates in. You can find all the seven numbers in the table below digit by digit and then know what is wrong with the ISE unit. 0 means no error. For example, when you see <0001000>, you only need to find where the “1” locates in the Digit 4 column and you will see it locates in the Na+ row. So you will know the + cause of this error is the noise in mV of Calibrant B or sample related to the Na electrode. Error

Digit 1

Digit 2

Digit 3

Digit 4

Digit 5

Digit 6

Digit 7

Air/ Hardwa re

mV Out

mV Out

Calib/S ample

Cal A in Calib/S ample Mode, Cal B in Urine Mode

mV Noise

mV Noise

Cal Drift

Cal B/Samp le


in Sample Mode, Cal B in Urine Mode

Out of Slope/ Machin e Ranges

S

0

0

0

0

0

0

Air in Calibrant A

A

0

0

0

0

0

0

Air in Calibrant B

B

0

0

0

0

0

0

Air in Cleaner

C

0

0

0

0

0

0

Air in Segment

M

0

0

0

0

0

0

Pump Calibration

P

0

0

0

0

0

0

No Flow

F

0

0

0

0

0

0

Bubble Detector

D

0

0

0

0

0

0

Reagent Read

Chip

R

0

0

0

0

0

0

Reagent Write

Chip

W

0

0

0

0

0

0

Store Calibration Value Error

Q

0

0

0

0

0

0

Command Error

T

0

0

0

0

0

0

No Error

0

0

0

0

0

0

0

Na+

0

1

1

1

1

1

1

Air Sample/Urine

in

7-14

A

Service Flow Error

Digit 1

Digit 2

Digit 3

Digit 4

Digit 5

Digit 6

Digit 7

Air/ Hardwa re

mV Out

mV Out

Calib/S ample


mV Noise

mV Noise

Cal Drift

Cal B/Samp le


in Sample Mode, Cal B in Urine Mode

Out of Slope/ Machin e Ranges

K+

0

2

2

2

2

2

2

Na+, K+

0

3

3

3

3

3

3

Li+

0

4

4

4

4

4

4

Li+, Na+

0

5

5

5

5

5

5

Li+, K+

0

6

6

6

6

6

6

Li+, K+, Na+

0

7

7

7

7

7

7

Cl-

0

8

8

8

8

8

8

Cl-, Na+

0

9

9

9

9

9

9

Cl-, K+

0

A

A

A

A

A

A

Cl-, Li+

0

B

B

B

B

B

B

Cl-, K+, Na+

0

C

C

C

C

C

C

Cl-, Li+, Na+

0

D

D

D

D

D

D

Cl-, Li+, K+

0

E

E

E

E

E

E

Cl-, Li+, K+, Na+

0

F

F

F

F

F

F

A

The following table displays the causes and the correction measures of some errors. Note that if the correction measure is the replacement of board, bubble detector or other components in the ISE unit, you have to replace the whole ISE unit. You can refer to the chapter 5 for detailed information about some replacement procedures.

Symptom System respond

Problem does

not

Correction

1. No power 2. Communication failure

Turn off the system and then start it again.

3. RS232 cable is disconnected or damaged.

Move the panel of analyzing unit and reconnect or replace cable between the ISE unit and the main control board.

4. Module connector has been damaged.

Replace board.

5. Component failure on board.

Replace board.

7-15

Service Flow Symptom

Problem

Correction

Low Slope

1. Misalignment of electrodes

Remove and replace electrodes <45 mV/decade to reseat properly.

2. Deterioration of calibrator solutions

Replace Calibrant B first and retest. If still low, replace Calibrant A and retest.

3. Deterioration of electrode (low slope)

Replace and test.

Na+, K+, or Li+ <45 mV/decade Cl- <35 mV/decade or High Slope Na+, K+, or Li+ >63 mV/decade

sensing

Single electrode

electrodes

4. Air bubble on reference electrode membrane

Remove electrode, tap to dislodge bubble, replace, and recalibrate.

5. Deterioration of reference electrode

Replace reference and retest.

6. Module or fluid temperatures exceed 37° C. (high slope)

Monitor temperature. Change instrument location if ambient is too great.

1. Deterioration electrode

Replace and test.

Cl- >60 mV/decade

Noise Error Flag

problem

of

sensing

2. Electrical noise spike from environmental source

problem

electrode

electrodes

a) Check for electrical noise coincident with activation. b) Check grounding of Module. c) Component failure on Module board. Replace board.

Noise Error Flag Multiple electrodes

1. Deterioration of reference electrode


electrode

2. Electrical noise spike from environmental source

a) Check for electrical noise coincident with activation. b) Check grounding of Module. c) Component failure on Module board. Replace board.

Drift Error Flag Single electrode

Drift Error Flag Multiple electrodes

1. May occur when new electrode or new bottle of Calibrant A is installed by system.

Purge the Calibrant A and recalibrate the module. If the electrode is new it may initially drift as it rehydrates over the course of 15 minutes.

2. Deterioration electrode

Replace the problem electrode and test.

of

sensing

1. May occur when new electrode or new bottle of Calibrant A is installed on system.

Purge Calibrant A recalibrate the Module.

2. Deterioration of reference electrode.


7-16

and

electrode


Problem

Correction

3. Electrical spike environmental source.

from

a) Check for electrical noise coincident with activation. b) Check grounding of Module. c) Component failure on Module board. Replace the board.

Air in Sample

1. Insufficient sample pipetted into Module sample entry port

a) Host instrument must deliver 70 µL. Increase dispensed volume. b) Operator must place sufficient sample in sample cup to account for all tests programmed. c) Fluid leak in electrodes.

2. Sample not positioned

a) Electrodes not seated sea ted properly. Reseat electrodes. b) Pump tubing aging. Replace. c) Pump tubing obstructed or tubing length is excessive.

Air in Sample Calibrant A

and

1. Sample and Calibrant A are segmented with air.

a) Electrodes are not properly seated or compressed. Check compression plate, spring and seal. Reseat electrodes. b) Ensure that all electrodes and o-rings are in place.

2. Fibrin or salt is plugging the electrode flow path.

a) Use Cleaning procedure for Module. b) Disassemble Module and clean or replace electrode with plugged flow path.

3. Bubble malfunctioning.

detector

4.Waste pump malfunctioning. Air in Calibrant B and Air in Calibrant A

is

Replace bubble detector.

is

Replace waste pump.

1. Calibrant B and Calibrant A are segmented with air.

a) Electrodes are not properly compressed. Check compression plate, spring and seal. b) Ensure that all electrodes and o-rings are in place. c) Ensure tubing is connected properly. d) Replace tubing.

7-17


Problem

Correction

2. Fibrin or salt is plugging the electrode flow path.

a) Use Cleaning procedure for Module. b) Disassemble Module and clean or replace electrode with plugged flow path.

Air in Calibrant A (no “Air” errors reported for Sample or Calibrant B)

3. Waste pump malfunction.

Replace waste pump, tubing.

4. Bubb Bubble le Detec Detector tor malfunc malfunctio tion. n.

Replac Replace e bubbl bubble e detec detector. tor.

1. Calibrant A pouch is empty.

Replace Calibrant A with a new one, purge and recalibrate.

2. Tubing is disconnected.

Reconnect or replace tubing.

3. Calibrant A pump is not working properly.

a) Check electrical connections. b) Replace pump tubing. c) Replace motor.

4. Tubing is plugged, split or crimped.

7-18

Replace tubing

Mechanical Structure

8 Mechanic Mechanical al Structu tru cture re

Reagent Reagent disk moto r

Synchronous belts

Coder sensors

8-1

Reaction Reaction disk motor


Reagent Reagent prob e assembly

Mixing bar assembly

Reagent Reagent coolin g assembly

8-2



Lamb assembly

Big head of fiber

Fan Fan of Lamb assembly

8-3


Reacti Reacti on dis k TEMP TEMP. control assembly assembly

Optical assembly

Small heads heads of f iber

Reference Reference light assembly

8-4


Washing assemblies

Reagent Reagent syri nge

Sample syringe

8-5

Valves

Pumps


A/D c on ver si on bo ard

Main Main cont rol board

Power drive board

Reagent Reagent refrigeration b oard

8-6


Loading system

Manipulator assembly

8-7


Top of mi xing assembly Top o f sample assembly

Top o f reagent assembly

Bar code scanner (optional)

8-8

Tools and Parts

9 Tools oo ls and Parts Parts 9.1 9.1

Serv Servic ice e Tools oo ls S/N

TOOL

Qu an t i t y

Sp ec if if i c at at i o n

Un i t

1

Allen Key

1 set

1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 5.0

mm

2

Phillips screwdriver

1 set

3*75, 5*75, 6*100

mm

3

Flat-bladed screwdriver screwdrive r

1 set

3*75, 5*75, 6*100

mm

4

Long Allen Key

1 set

2.5, 3.0

mm

5

Tweezers

1 pair

small

/

6

Multimeter Multimete r

1

common

/

7

Movable Wrench

1

common

/

8

Electric Electri c iron

1

30

VA

9

Stainless Stainles s steel

1

0.5 (diameter), (length)

10

Knife

1

common

/

11

Pincers

1

common

/

9.2

15

mm

Parts

S/N

P/N

Name

1

BA30-20-06448

Cable for reagent probe assembly’s elevator motor

2

BA30-20-06449

Cable for reagent probe assembly’s rotary motor

3

BA30-20-06450

Cable for Sample syringe’s motor

4

BA34-20-63601

Cable for Reagent syringe’s motor

5

BA30-20-06452

Cable for sample probe assembly’s elevator motor

6

BA30-20-06453

Cable for sample probe assembly’s rotary motor

7

BA30-20-06454

Cable for mixing bar assembly’s rotary motor

8

BA30-20-06455

Cable for mixing bar assembly’s elevator motor

9

BA30-20-06458

Cable for reagent compartment motor

10

BA30-20-06459

Cable for sample compartment motor

11

BA34-20-63602

Cable for reaction compartment motor

12

BA30-20-06464

Cable for loading system motor

13

BA30-20-06468

Cable for Sample and reagent valves

9-1

Tools and Parts S/N

P/N

Name

14

BA30-20-06476

26-pins sensor cable

15

BA30-20-06477

34-pins sensor cable

16

BA30-20-06480

Detection Detectio n cable for reaction compartment’s fan

17

BA30-20-06481

Cable between CPU board and power drive board

18

BA30-20-06484 BA30-20-06484

Cable for waste and distill water container

19

BA30-20-06485

Cable between CPU board and loading system

20

BA34-20-63651

Cable between CPU board and manipulator

21

BA30-20-06523

Temperature sensor cable of reagent cooling system

22

BA30-20-15291

Cable between CPU board and reagent detection detectio n board

23

BA30-20-15292

Cable between CPU board and sample detection detectio n board

24

BA34-20-63603

Cable between power drive board and mixing motor

25

BA34-20-63631

Reagent probe cable

26

BA30-20-15295

Sample probe cable

27

BA30-20-15296

Mixing bar cable

28

A21-000010---

Tubing

29

BA30-10-15051

Single-way valve

30

0040-10-32303

Tubing

31

0040-10-32304

Connector

32

0040-10-32305

Connector

33

M90-100014---

1/4-28 UNF LOCK NUT-RED NYL LNS-3

34

M90-100015---

1/4-28 UNF LOCK NUT-RED N NYL LNS-4

35

M90-100030---

1/8 Y BARBED FITTING-WHITE FITTING-W HITE NYL Y230-

M90-100050---

BULKHEAD MOUNTED FEMALE LURE RED NYLON CCLR-3

M90-100051---

BULKHEAD MOUNTED FEMALE LURE GREEN NYLON CCLR-4

38

M90-100071---

Tubing

39

BA30-30-15169

5-way connector

40

BA30-10-06666

Step motor

41

BA30-10-15041

synchronous belt (220 XL037)

42

BA30-10-15258

Door’s magnet (couple)

43

BA34-30-63559

Power drive board

44

BA30-30-06312

Reagent cooling control board

45

BA34-30-63613

Sample compartment assembly

36 37

9-2

Tools and Parts S/N

P/N

Name

46

BA30-10-06365

Halogen Lamb (50W)

47

BA30-30-06691

REF pre-amplification pre-amplific ation board

48

BA30-30-15228

340nm amplification amplific ation assembly

49

BA30-10-06367

Filter 340

50

BA30-30-06673

340nm pre-amplification pre-amplifi cation board

51

BA30-30-15229

405nm pre-amplification pre-amplifi cation assembly

52

BA30-10-06368

Filter 405

53

BA30-30-06675

405 pre-amplification pre-amplific ation board

54

BA30-30-15230


55

BA30-10-06369

Filter 450

56

BA30-30-06677


57

BA30-30-15231


58

BA30-10-06370

Filter 510

59

BA30-30-06679


60

BA30-30-15232


61

BA30-10-06371

Filter 546

62

BA30-30-06681


63

BA30-30-15233


64

BA30-10-06372

Filter 578

65

BA30-30-06683


66

BA30-30-15234


67

BA30-10-06373

Filter 630

68

BA30-30-15235


69

BA30-30-15235


70

BA30-10-06374

Filter 670

71

BA30-30-06687


72

BA30-30-15236


73

BA30-10-06375

Filter 700

74

BA30-30-06689


75

BA30-30-06565

Drive assembly of sample probe

76

BA34-30-63637

Syringe assemply

77

3100-10-49438

100ul Syringe

78

BA30-10-06651

500ul Syringe

79

BA30-10-15115

Step motor

9-3

Tools and Parts S/N

P/N

Name

80

BA30-20-06594

3-way connector for syringe

81

BA30-21-15161

Sensor cable for reagent syringe

82

BA30-21-15162

Sensor cable for sample syringe

83

BA30-30-06634

Mixing bar assembly

84

BA30-21-15159

Cable for mixing bar assembly’s elevator motor

85

BA30-21-15160

Cable for mixing bar assembly’s rotary motor

86

BA30-30-06639

Fans of lamb assembly

87

BA30-30-06641

Washing pool assembly

88

0040-10-32302

Connector

89

0040-10-32303

Washer

90

BA30-21-15311

Valves assembly (KNF)

91

BA30-30-06702

Reaction compartment assembly

92

BA30-30-06715

A/D converter assembly

93

BA30-30-06752

Rocker of reagent probe

94

BA30-30-06304

Liquid detection board

95

BA30-30-06753

Reagent probe assembly

96

BA30-30-06761

Heat-block Heat-bloc k assembly

97

BA30-30-06768

Rocker of sample probe

98

BA30-30-14978


99

BA30-30-06770

Rocker of mixing bar

100

BA34-20-63653

Loading system assembly

101

BA30-21-06488

Pressure sensor and cable for loading system

102

BA30-21-06490 BA30-21-06490

Cable for cuvette-pushing cuvette-pushing limit transducer

103

BA30-21-06491

Cable for cuvette-taking cuvette- taking limit transducer

104

BA30-21-06492 BA30-21-06492

Cable for insufficient-cuvette insufficient-cuvette transducer

105

BA34-20-63648

Board for loading system

106

BA30-21-06489

Cable for no-cuvette no-cuvett e transducer

107

BA30-30-15034

Code sensor of reaction compartment

108

BA30-30-15095

Reagent compartment assembly

109

BA30-30-06780

Reagent disk handle assembly

110

BA30-30-15113

Driving assembly of reagent probe

111 111

BA30-21-15155

Sensor cable for reagent probe’s up-down sensor

112

BA30-21-15156

Sensor cable for reagent probe’s rotary sensor

113

BA30-30-15166

Coder sensor for reagent disk

9-4

Tools and Parts S/N

P/N

Name

114

BA30-30-15167

Coder sensor for sample probe’s sensor

115

BA30-30-15284

Probes connection board

116

BA34-30-63557

Main control board

117

BA33-30-35098

Power supply module

118

BA33-30-35078

PFC Board

119

BA33-30-35082

24V Board

120

BA33-30-35080

12V&5V Board

121

TSB1-20-20399

Fan

122

BA34-20-63655

Manipulator assembly

123

BA33-30-35223

Power socket and switch assembly

124

BA34-20-63622

Reagent temperature control assemply (220V)

125

BA34-20-63614

Cover of sample compartment

126

BA30-30-15029

Cover of reagent compartment

127

BA34-20-63638

Reagent temperature control assemply (110V)

9-5

Maintenance And Test Software

10

Main Maintenance tenance And An d Test Software

10.1 General The maintenance and test software of the BS-300 Chemistry Analyzer is the software that helps maintenance personnel debug and maintain the BS-300 Chemistry Analyzer. Maintenance personnel can, through this software, check whether the probes, mixing bar, disks, fluidic system and photometric system of the BS-300 Chemistry Analyzer work normally, modify parameters, and execute individual commands or combined commands. Run the NewDebug.exe NewDebug.exe file to enter the Maintenance and Test window. See Figure 10-1.

Figure 10-1 Maintenance and Test window

Display Area

As shown in Figure 10-1, there are 4 tabs in the Maintenance and Test window: 

Command



PARA an d Speed



Temperature



Photoelectric

10-1


Note: The buttons displayed in gray in software interface are not functional.

Following is a brief introduction to the software interface. 

Display area

At the bottom of the window is the display area for displaying the frame information and fault/error information. The upper box is for frame information, and the lower one is for fault/error information. There are five types of frame information, including Result, Result , Echo, Echo , Data, Data, Command and Command and Warning. Warning . Select the check box in front of frame information to display relevant frame information. Click the check box again to de-select, and the frame information will not be displayed. Click the Clear button button to clear the information displayed in relevant box. The two Clear buttons buttons are respectively for two boxes. 

Setup button

Click the Setup button at up right corner to show a dialog as shown in Figure 10-2, which is used to change communication port and set baud rate and check sum type of the port. Check sum type includes odd, even and none.

Figure 10-2 Serial Port Setup Communication Port

Baud Rate



Check Sum Type

Ab out… ou t… button button

Clicking the Ab the Ab out… ou t… button at up right corner of the interface, you can view the version information of this software. In the following sections, the 4 tabs mentioned above will be detailed respectively.

10-2


Note: The units of parameters involved in this software are respectively: Time: 50ms; Sample (reagent) aspirating/dispensing volume: steps of motors; Temperature: ℃. Temperature control coefficient: 0.01.

10.2 Command In the Command Command tab, you can send commands to the analyzing unit and check whether probes, mixing bar, disks, fluidic system, photometric system, ISE unit and built-in bar code scanner work normally.

Figure 10-3 Command tab Command tab Single Command Area

Macroinstruction Area

As shown in Figure 10-3, the Command tab Command tab mainly consists of two parts: Single Command Area and Macroinstruction Area.

10.2 10.2.1 .1 Singl e Command Area Ar ea In Single Command Area, there are 8 sub-tabs: 

Main Unit



Reagent Reagent Uni t



Sample Unit

10-3

Maintenance And Test Software 

Load Unit



Temp Unit



Photoelectric Photoelectric Unit



ISE Module



Sample Bar Code Module

Check the analyzing unit for their counterparts. There are several buttons in each tab. Click a button and you can send a command to the counterpart on the analyzing unit.

Note: After starting this software, you must click the Download parameters to Analyzing Unit button in the Main Unit Unit sub-tab. Otherwise, the software will not operate the analyzing unit successfully. After clicking the Enable modifying parameters button in the Main Unit Unit sub-tab, you can modify the parameters in the PARA and Speed tab. Speed tab.

Following are instructions to the action implemented by each command. 

Main Unit

Command

What it does

Download parameters Analyzing Unit

to

Configures running analyzing unit.

parameters

for

the

Reset all mechanical parts

Moves all units of the analyzing unit to their initial position, and cleans reagent probe, sample probe and mixing bar.

Enable parameters

modifying

Switches on the switch for modifying parameter through this operation before modifying parameter at PARA and Speed tab. Speed tab.

Disable parameters

modifying

Switches off the switch for modifying parameter through this operation after modifying parameter at PARA and Speed tab. Speed tab.

Handshake with Analyzing Unit

Checks that the communication cable works normally.

Send a direct instruction

Edits and sends user-defined commands.



Reagent Reagent Uni t

Command

What it does

Reagent probe wash

Cleans the reagent probe.

Pump, valve (interior) on

Turns on the pump and the valves that control flow of washing the interior of reagent probe.

10-4

Maintenance And Test Software Command

What it does

Pump, valve (interior) off

Turns off the pump and the valves that control flow of washing the interior of reagent probe.

Pump, valve (exterior) on

Turns on the pump and the valve that control flow of washing the exterior of reagent probe.

Pump, valve (exterior) off

Turns off the pump and the valve that control flow of washing the exterior of reagent probe.

Probe above reaction disk

Moves the reagent probe above the reaction disk.

Probe above outer circle

Moves the reagent probe above the outer circle of reagent disk.

Probe above inner circle

Moves the reagent probe above the inner circle of reagent disk.

Probe tip above bottle top (outer circle)

Moves the reagent probe until the probe tip a few millimeters above the top of the reagent bottle in the outer circle of reagent disk.

Probe tip above bottle top (inner circle)

Moves the reagent probe until the probe tip a few millimeters above the top of the reagent bottle in the inner circle of reagent disk.

Probe down to outer circle

Moves the reagent probe down to the reagent bottle in the outer circle of reagent disk.

Probe down to inner circle

Moves the reagent probe down to the reagent bottle in the inner circle reagent disk.

Probe down to reaction disk

Moves the reagent probe down to the cuvette in the reaction disk.

Probe tip above cuvette top

Moves the reagent probe until the probe tip a few millimeters above the top of cuvette in the reaction disk.

Probe down to wash well

Moves the reagent re agent probe to its washing position.

Probe above wash well

Moves the reagent probe to the top of wash well.

Reagent disk rotate

Rotates the reagent disk for specified circles and stop it at specified bottle position. Input rotating circles in the first box and position No. in the second box.

Reagent position

disk

rotate

to

Rotates the reagent disk to specified bottle position. Input position No. in the box.

Reagent syringe init

Moves the reagent syringe to its initial position.

Reagent syringe full

Moves the reagent syringe to its largest travel.

Reagent syringe empty

Empties the reagent syringe.

Reagent unit reset

Cleans the reagent probe and rotates the reagent disk to position No. 1.

10-5


Sample Unit

Command

What it does

Sample probe wash

Cleans the sample probe.

Pump, valve (interior) on

Turns on the pump and the valves that control flow of washing the interior of sample probe.

Pump, valve (interior) off

Turns off the pump and the valves that control flow of washing the interior of sample probe.

Pump, valve (exterior) on

Turns on the pump and the valve that control flow of washing the exterior of sample probe.

Pump, valve (exterior) off

Turns off the pump and the valve that control flow of washing the exterior of sample probe.

Probe above wash well

Moves the sample probe to the top of wash well.

Probe above reaction disk

Moves the sample probe to the top of reaction disk.

Probe above outer circle

Moves the sample probe above the outer circle of sample disk.

Probe above inner circle

Moves the sample probe above the inner circle of sample disk.

Probe tip above tube top (outer circle)

Moves the sample probe until the probe tip a few millimeters above the top of the tube in the outer circle of sample disk.

Probe tip above tube top (inner circle)

Moves the sample probe until the probe tip a few millimeters above the top of the tube in the inner circle of sample disk.

Probe tip above cuvette top

Moves the sample probe until the probe tip a few millimeters above the top of cuvette in the reaction disk.

Probe down to reaction disk

Moves the sample probe down to the reaction cuvette in reaction disk.

Probe down to wash well

Moves the position.

Probe down to outer circle

Moves the sample probe down to the tube in the outer circle of sample disk.

Probe down to inner circle

Moves the sample probe down to the tube in the inner circle of sample disk.

Sample disk rotate

Rotates the sample disk for specified circles and stop it at specified tube position. Input rotating circles in the first box and position No. in the second box.

Sample position

disk

rotate

to

sample probe

to its

washing

Rotates the sample disk to specified tube position. Input position No. in the box.

Sample syringe init

Moves the sample syringe to its initial position.

Sample syringe empty

Empties the sample syringe.

Sample syringe full

Moves the sample syringe to its largest travel.

10-6


What it does

Sample unit reset

Cleans the sample probe and rotate the sample disk to position No. 1.



Load Unit

Command

What it does

Mixer Mixer to the top top of wash wash well well

Moves Moves the the mixing mixing bar bar to the the top top of wash wash well well..

Mixer move into wash well

Moves the mixing bar to its washing position.

Mixer move to the top of reaction disk

Moves the mixing bar to the top of reaction disk.

Mixer disk

Moves the mixing bar to mixing position in reaction disk.

move

into

reaction

Mixer stir for a while

Mixing bar stirs for a specified period.

Mixing bar rotates for a while above wash well

Moves the mixing bar above its wash well and then rotates it for a specified period.

Take new cuvettes

Moves the compartment trolley backwards to get new cuvettes.

Load New cup

Rotates the reaction disk to specified position, then get new cuvettes with the manipulator and put them in reaction disk.

Unload cup

Rotates the reaction disk to specified position, then get the cuvettes in reaction disk with the manipulator and put them in used-cuvette bucket.

Motion Motion of manipulator manipulator fingers

Tightens Tightens or loosen manipulator’s manipulator’s (grabbing mechanism).

fingers

After entering a value of 0-3 to the box, click the button and the fingers will motions. 0 means both fingers tighten; 1 means the upper loosen and the lower tightens; 2 means the upper tightens and the lower loosens; and 3 means both loosen. Manipulator to vertical init. pos.

Moves the position.

Manipulator pos.

init.

Moves the manipulator to horizontal initial position.

To H-pos. H-pos. for taking taking cuvettes cuvettes

Moves the manipul manipulator ator to to horizontal horizontal position position for getting cuvettes.

To V-pos. for taking cuvettes cuvettes

Moves the manipulat manipulator or to vertical position position for getting cuvettes.

To H-position cuvettes

for

placing

Moves the manipulator to horizontal position for placing cuvettes.

To V-position cuvettes

for

placing

Moves the manipulator to vertical position for placing cuvettes.

to

horiz.

10-7

manipulator

to

vertical

initial


What it does

Move steps vertically

Moves the manipulator for specified steps in vertical way wa y.

Move steps horizontally

Moves the manipulator for specified steps in horizontal way. way.

Loader unit reset

Moves the mixing bar to its initial position, loosen manipulator’ grabbing mechanism and move the manipulator to its initial position.



Temp Uni t

Command

What it does

Temperature control on

Turns on controller(s).

the

specified

temperature

There’re two temperature controllers Reaction Disk and Disk and Reagent Pr eHeat eHeat .

as

Selects the check box(es) in front of a controller(s), click the button, you can turn on the selected controller(s). Temperature control off

Turns off controller(s).

the

specified

temperature

There’re two temperature controllers Reaction Disk and Disk and Reagent Pr eHeat eHeat .

as

Selects the check box(es) in front of a controller(s), click the button, you can turn off the selected controller(s).



Photoelectric Photoelectric Unit

Command

What it does

Reaction disk rotate

Rotates the reaction disk for specified circles and stop it at specified cuvette position. Input rotating circles in the first box and position No. in the second box.

Reaction disk rotate some positions

Rotates the reaction disk for specified cuvette positions, and input number of cuvette positions in the box.

Rotate and measure

Rotates the reaction disk, collects reaction data during rotating, and then stops it at specified cuvette position.

Turn on light

Turns on the light.

Turn off light

Turns off the light.

Test dark current

Turns off the light and measures the dark current at this time. The dark current data will be displayed in the box below.

10-8


What it does

Test base current

Unloads the first segment of cuvettes in reaction disk with manipulator, then rotates the reaction disk and during rotating measures the light where places the first segment of cuvettes before. The data regarding base current will be displayed in the box below.



ISE Module

Command

What it does

Handshake

The ISE unit shakes hands with the main unit.

Maintain

Executes the maintaining cycle to run the waste pump until the electrode flow path is cleared of fluid.

Detect Bubble

Checks to see if the bubble detector is functioning properly.

Cleaning Period

Removes protein build-up from the ISE Module electrodes.

Calibrate

Calibrates the electrodes of the ISE Module.

Correct Pumps

Calibrates the peristaltic pumps of the ISE Module.

Measure Serum

Measures serum or plasma samples on the ISE Module.

A Purge

Purges Calibrant A solution through the tubing from the pouch of Calibrant A to the ISE Module.

B Purge

Purges Calibrant B solution through the tubing from the pouch of Calibrant B to the ISE Module.

Pumps 200µl of Calibrant A to make it convenient for you to aspirate it from the sample entry port.

Displays the result of bubble detector checking for the last time.

Displays the result of pump correction for the last time.

Displays the software version of the ISE unit.

After clicking this button, the results in mv will also be displayed when calibration, measurement or a sip cycle is finished.

After clicking this button, the results in mv will also be displayed when calibration or measurement is finished.

Disables the effect of clicking or .



Sample Bar Code Module

Command

What it does

Set

Select a symbology from the pull down list and click this button. If Valid is Valid is selected, the symbology will be set as the one that the scanner can recognize. Otherwise, it will be the one that can not be recognized.

10-9


What it does

Send

Enter an instruction into the edit box and click this button to send it to the analyzing unit.

Laser On

Turns on the laser of the bar code scanner.

Laser Off

Turns off the laser of the bar code scanner.

Handshake

The bar code scanner shakes hands with the main unit.

Scan

After entering the start position No. and the end one into Start Start and End End edit boxes respectively, click this button to scan bar codes on the selected positions.

10.2 10.2.2 .2 Macro Macro ins tru cti on A rea Figure 10-4 Macroinstruction Area Explanation for the macroinstruction

Macroinstruction

Commands

Button

Parameters of the current command

A macroinstruction macroinstruction is a set of commands. When selecting a macroinstruction from the pulldown list in macroinstruction area, you can see there’re various commands and comments regarding the macroinstruction. In addition, parameters of the command currently selected will also be displayed on the interface. In the macroinstruction area, after selecting a macroinstruction from the pulldown list, you can 

Click the Run button to run the selected macroinstruction;

10-10


Click the Pause button Pause button to suspend the macroinstruction which is running;



Click the Stop button Stop button to stop the macroinstruction which is running.

Note: After all commands in each macroinstruction are executed, the system counts it as one time. When the check box on the right of the macroinstruction pulldown list is selected, the selected macroinstruction will be executed for once; otherwise, the macroinstruction will be executed cyclically.

For each macroinstruction, the commands of it are executed one by one in the sequence in which they are listed. When the set delay expires after a command is executed, the next command is executed immediately. In case of an error in the execution process, the macroinstruction will be stopped. Following are instructions to the action implemented by each macroinstruction. Macroinst Macroinst ruction

Command Command

What What it does

A,B purge

B purge

Purges Calibrant B solution through the tubing from the pouch of Calibrant B to the ISE Module.

A purge

Purges Calibrant A solution through the tubing from the pouch of Calibrant A to the ISE Module.

Reagent probe above wash well

Moves the reagent above its wash well.

Valve on, Pump on

Turns on the pump and valve that control the flow of washing the exterior of reagent probe.

Pump off, Valve off

Turns off the pump and valve that control the flow of washing the exterior of reagent probe.

Sample probe above wash well

Moves the sample above its wash well.

Valve on, Pump on

Turns on the pump and valve that control the flow of washing the exterior of sample probe.

Pump off, Valve off

Turns off the pump and valve that control the flow of washing the exterior of sample probe.

Check exterior fluid path of reagent probe

Check exterior fluid path of sample probe

10-11

probe

probe

Maintenance And Test Software Macroinst Macroinst ruction

Command Command

What What it does

Check interior fluid path of reagent probe

Reagent probe above wash well

Moves the reagent above its wash well.

Valve on, Pump on

Turns on the pump and valves that control the flow of washing the interior of reagent probe.

Pump off, Valve off

Turns off the pump and valves that control the flow of washing the interior of reagent probe.

Sample probe above wash well

Moves the sample above its wash well.

Valve on, Pump on

Turns on the pump and valves that control the flow of washing the interior of sample probe.

Pump off, Valve off

Turns off the pump and valves that control the flow of washing the interior of sample probe.

Test Loader

Reload cup looply

The manipulator gets new cuvettes from the compartment looply, and then put them in the reaction disk.

Test mixing bar in reaction disk

Reaction disk to next cup

The reaction disk rotates and stops. No. of position for reaction disk to stop at will increase.

Mix instruction

The mixing bar moves into reaction cuvette and mixes for a specified period.

Mixer to vertical init

The mixing bar moves to vertical initial position.



Reagent probe reaction disk

to

The reagent probe moves vertically into bottom of reaction cuvette.

Reagent probe vertical init

to

The reagent probe moves to vertical initial position.



Check interior fluid path of sample probe

Test reagent probe in reaction disk

Test sample probe in reaction disk

10-12

probe

probe

Maintenance And Test Software Macroinst Macroinst ruction

Urine test diluted)

(auto

Urine test (manually diluted)

Command Command

What What it does

Sample probe reaction disk

to

The sample probe moves vertically into bottom of reaction cuvette.

Sample probe vertical init

to

The sample probe moves to vertical initial position.

Reagent disk in position 50 in next period

Reagent disk rotates to position 50 and in the next period the reagent probe will aspirate urine diluent from the position.

Dispensing 270µl urine diluent

of

Reagent probe aspirates 207µl of urine diluent and dispenses it to a cuvette.

Dispensing 30µl urine sample

of

Sample probe aspirates 30µl of urine sample and dispenses it to a cuvette. The mixing bar stirs it.

Washing mixing bar

Washes the mixing bar.

First period

Sample probe aspirates 70µl of diluted urine to the ISE unit.

Second period


Third period

Washes the sample probe.

Idle period

Measuring.

Idle period

Measuring.

Idle period

Measuring.

First period


Second period


Third period

Washes the sample probe.

Idle period

Measuring.

Idle period

Measuring.

Idle period

Measuring.

10.3 10.3 PARA and Speed In the PARA and Speed tab, Speed tab, you can query, configure or load parameters as well as debug the units.

10-13

Maintenance And Test Software Figure 10-5 PARA and Speed tab Parameters

Buttons

As shown in Figure 10-5, the PARA and Speed tab Speed tab mainly consists of two parts as unit parameter and several operating buttons. Unit Name includes Name includes Main unit, unit , Sample unit , Reagent unit, unit , Photoelectric unit , Temp un it and Load unit. unit . At this screen, you can not only inquire and configure each unit parameters, but also save and read relevant data. Now let’s introduce them respectively. 

Inquire unit parameters

1

Select a unit in Unit Name. Name.

2

Click Query button. Query button. For example.

10-14




Configure a parameter for a unit

1


2

Click the Query button. Query button.

3

Edit the parameter if necessary. Otherwise, go to the next step directly. When editing, you can directly select and modify the data to be edited.

4

Select a parameter to be configured. For example.

5

Click the Config button Config button to configure the parameter for relevant unit of the analyzing unit.



Configure all parameters for relevant units

1

Select units in Unit Name. Name.

2

Click the Config All button All button to configure all parameters of the selected unit for relevant units of the analyzing unit.



Save data

1


2

Click the Save button, Save button, then pop up a dialog.

3

Input a filename and click the Save button, Save button, you can save parameters of the currently selected unit to a .txt file.



Read Data

1

Click Load button, Load button, then pop up a dialog.

2

Select the relevant .txt file and click Open Open button, you can configure parameters in the file for relevant unit of the analyzing unit.

The following contents explain the adjustable parameters.

10-15


Reagent unit

Para Paramete meterr

Unit

Default Default

What What the param paramete eterr means means

H-pos. for washing reagent probe

Whole step

42

Position correction of the reagent probe in the horizontal direction when it is above its wash well.

H-pos. of reaction disk

Whole step

-42

Position correction of the reagent probe in the horizontal direction when it is above the reaction disk.

H-pos. of reagent disk inner circle

Whole step

215

Position correction of the reagent probe in the horizontal direction when it is above the inner circle of reagent disk.

H-pos. of reagent disk outer circle

Whole step

165

Position correction of the reagent probe in the horizontal direction when it is above the outer circle of reagent disk.

Position correction of reagent disk inner circle

Micro step

10

The position correction of the reagent disk when it stops at the specified position according to the position No. of its inner circle.

Position correction of reagent disk outer circle

Micro step

10

The position correction of the reagent disk when it stops at the specified position according to the position No. of its outer circle.

Para Paramete meterr

Unit

Default Default


Bar code position correction of sample disk inner circle

Micro step

18

Position correction of the inner circle of sample disk relative to the outer circle when the bar code scanner scans specified positions.

H-pos. for washing sample probe

Whole step

102

Position correction of the sample probe in the horizontal direction when it is above its wash well.

H-pos. of sample disk inner circle

Whole step

202

Position correction of the sample probe in the horizontal direction when it is above the inner circle of sample disk.

H-pos. of sample disk outer circle

Whole step

165

Position correction of the sample probe in the horizontal direction when it is above the outer circle of sample disk.



Sample unit

10-16

Maintenance And Test Software Para Paramete meterr

Unit

Default Default


H-pos. of sample probe in reaction disk

Whole step

-106

Position correction of the sample probe in the horizontal direction when it is above the reaction disk.

H-pos. of sample probe in ISE

Whole step

490

Position correction of the sample probe in the horizontal direction when it is above the sample entry port of ISE unit.

Position correction of sample disk inner circle

Micro step

10

The position correction of the sample disk when it stops at the specified position according to the position No. of its inner circle.

Position correction of sample disk outer circle

Micro step

10

The position correction of the sample disk when it stops at the specified position according to the position No. of its outer circle.

V-pos. of sample probe in ISE

Whole step

163

Position correction of the sample probe in the vertical direction when it is above the sample entry port of ISE unit.

Parameter

Unit

Defa efault

Wha What the the para parame mete terr me means

Manipulator h-position for placing cuvettes

Whole step

70

Position correction of the manipulator in horizontal direction when it places a cuvette segment into the reaction disk.

Manipulator h-position for taking cuvettes

Whole step

259

Position correction of the manipulator in horizontal direction when it takes a cuvette segment from the cuvette compartment.

Manipulator v-position for placing cuvettes

Whole step

70

Position correction of the manipulator in vertical direction when it places a cuvette segment into the reaction disk.

Manipulator v-position for taking cuvettes

Whole step

768

Position correction manipulator in vertical when it takes a segment from the compartment.

Mixing bar h-position for washing

Whole step

68

Position correction of the mixing bar in the horizontal direction when it is above its wash well.



Load unit

10-17

of the direction cuvette cuvette

Maintenance And Test Software Parameter

Unit

Defa efault


Mixing bar h-position for mixing

Whole step

70

Position correction of the mixing bar in horizontal direction when it is above the reaction disk.

Unit

Defa efault




Photoelectric unit

Parameter Photoelectric parameter 405

gain

/

127

Signal gain coefficient of A/D conversion for wavelength of 405nm.

Photoelectric parameter 450

gain

/

127



gain

/

127



gain

/

127



gain

/

127



gain

/

127



gain

/

127



gain

/

127


Photoelectric gain parameter reference light

/

127

Signal gain coefficient of A/D conversion for wavelength of reference light.


/

127


Micro step

25

Correction of the start position when photoelectric collection starts.

gain

Start position of photoelectric collection

10-18


10.4 Temperature Figure 10-1 Temperature tab

Reagent Temperature Curve Control Panel

Reaction Tray Temperature Curve Control Panel

The Temperature tab Temperature tab consists of two parts: 

Curve of reagent preheated temperature (upper part);



Curve of reaction disk (lower part).

The two temperature curves are controlled respectively through two control panels on the right. Meanings of the parameters on the control panels are as follows. Parameter Parameter

What it does

Value

Displays current temperature value on the temperature curve.

YRange

Temperature range on Y-coordinate of the temperature curve. Input upper limit and lower limit of temperature range in the two boxes.

XRange

X-coordinate point of the temperature curve.

Temp

Intended temperature expected to achieve.

Period

Interval for sampling.

After setting Xrange, Xrange, Yrange and Yrange and Temp on Temp on the control panel, click Confirm button Confirm button to implement them on relevant temperature curve. There are 4 more buttons in each of the two control panels: 

Start: Start : After setting Period setting Period,, clicking it, you can start collecting the temperature data;

10-19


Stop: Stop : Clicking it, you can stop collecting the temperature data;



Freeze: Freeze : Clicking it, you can freeze the displayed curve;



Resume: Resume: Clicking it, you can resume the frozen curve.

10.5 Photoelectric In the Photoelectric Photoelectric tab, the values of photoelectric data and photoelectric data curve of the selected wavelength are displayed.

Photoelectric tab Figure 10-2 Photoelectric tab Display minimum data of each wavelength

Display maximum data of each wavelength

Display difference between the above two

Display all data Panel Display curve

Through the panel, you can set relevant parameters of photoelectric test data and photoelectric curve. Nine wavelengths (340, 405, 450, 510, 546, 578, 630, 670 and 700) and a base wavelength are listed on the control panel. You can select one of them to display its photoelectric data curve. Parameter Parameter

What it does

MinMax

Displays maximum and minimum for photoelectric data of the selected wavelength.

YRange

Range on the Y-coordinate of the curve. Input upper limit and lower limit for photoelectric data in the two boxes.

XRange

X-coordinate point of the curve.

CupIndex

Specifies the cuvette in certain position of reaction disk to be used to measure photoelectric data.

Dozes-reagent

Reagent dispensed to the specified cuvette.

Dozes-sample

Sample dispensed to the specified cuvette.

Period

Interval for sampling.

10-20

Maintenance And Test Software Parameter Parameter

What it does

Times

The times of sampling.

Mixer Mixer sti r

Select it to stir the reaction mixture; otherwise the reaction mixture will not be stirred.

Reaction Reaction disk rotate

Select it to enable the reaction disk to rotate during measurement with photoelectric data of all wavelengths displayed; otherwise the reaction disk will not be rotated and only photoelectric data of the selected wavelength will be displayed.

Through the control panel, you can select parameters like Wavelength, Wavelength, MinMax, MinMax , YRange, YRange, CupIndex and CupIndex and Period. Period . Moreover, you can select Mixer Mixer sti r as as required. After setting them, click the Confirm button Confirm button to confirm the settings. There are 6 more buttons in the panel: 

Start: Start : Clicking it, you can start collecting the temperature data;



Stop: Stop : Clicking it, you can stop collecting the temperature data;



Freeze: Freeze : Clicking it, you can freeze the displayed curve;



Resume: Resume: Clicking it, you can resume the frozen curve;



Save: Save: Clicking it, you can save the photoelectric data of all current wavelengths as a .txt file;



Load: Load : Clicking it, you can read the data in a .txt file saved with photoelectric data.

10-21

Boards Connection Diagrams

Ap A p p end en d i x A

B o ard ar d s Con Co n n ect ec t i o n Diag Di agrr ams am s Manipulator connection board

Power supply assembly


Main control board

Power drive board

A/D conversion board

Probes connection board

Feeder connection board

A-1


M42-M43: Refrigeration fan 2100-20-06534

C35: Reagent refrigeration temperature transducer BA30-21-15175

D N G e u l b 2 3 2 5 6 e 0 l b a 0 2 C 0 3 A B e u l b 1

J88

Cable BA30-20-06535

R E 3 I T 3 6 L 6 E P 0 : 1 0 3 2 0 M - 0 0 1 3 2 M

12V GND 12V GND

1

D V N 2 G 1 e d u e l r b 1 2

V 2 1 d e r 1

9 2 5 6 e 0 l b a 0 2 - D C 0 3 N A G B

d e r 2

2

J81

1

2

J79

1

2

J80

1

2

J78

1

2

J82

1

2

J83

1

2

D V N 2 G 1 e d u e l r b 1 2

V 2 1

D N G

V 2 1

e u l b 1

d e r 2

e u l b 1

d e r 2

1

2

1

2

J84

J85

J89 1 red

3 red 4 black

J86

12V

1

2 black

12&5V board BA33-30-35080

12V

2

COOLER

3

12V

4

GND

Reagent refrigeration board BA30-30-06312

GND

COOLER

GNDFAN 12FAN

J74

1

2

3

1

2

3

1

2

3

1

2

3

w o l l e y 1

e u l b 2

d e r 3

w o l l e y 1

e u l b 2

d e r 3

w o l l e y 1

e u l b 2

d e r 3

w o l l e y 1

e u l b 2

d e r 3

N A F

V 2 1

D N G

N A F

V 2 1

D N G

N A F

V 2 1

D N G

N A F

V 2 1

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

4 2 5 D 6 e 0 l - N G b a 0 2 C 0 3 A w B o l l e y 3 3

2

1

J73

3

2

1

J72

3

2

1

J71

3

2

1

J75

1

2

1

2

e u l b 1 5 2 5 6 e 0 l b D a 0 2 - N C 0 3 G A B

d e r 2

e u l b 1

d e r 2

V 2 1

D N G

V 2 1

d e r 1

e u l b 2

d e r 1

e u l b 2 2

1

J76

2

1

J77

1

2

e u l b 1

d e r 2

e u l b 2

d e r 1 2

1

J87

1

2

3

k c a l b 1

e t i h w 2

d e r 3

N A F

V 5

e t i h w 2

d e r 3

2

3

0 8 4 6 e 0 l - D b N a 0 2 - G C 0 3 A B k c a l b 1 1

J42 M37-M38: Fans on sides of lamp housing 2100-20-08114

M24-M27: Reaction temperature fan BA30-21-06530

A-5

Fan on rear side of lamp housing

4 yellow

P353

5

5 yellow

4

1

4

1 blue 5

2

6

3

6

12V

Main control board BA34-30-63557

Cable BA30-20-15308

3

2 blue

2

3 white

1

6 orange


M42-M43: Refrigeration fan 2100-20-06534

C35: Reagent refrigeration temperature transducer BA30-21-15175

D N G e u l b 2 3 2 5 6 e 0 l b a 0 2 C 0 3 A B e u l b 1

J88

Cable BA30-20-06535

R E 3 I T 3 L 6 E 6 P 0 : 1 0 3 2 0 M - 0 1 0 2 3 M

12V GND 12V GND

1

D V N 2 G 1 e d u e l r b 1 2

V 2 1 d e r 1

9 2 5 6 e 0 l b a 0 2 - D C 0 3 N A G B

d e r 2

2

J81

1

2

J79

1

2

J80

1

2

J78

1

2

J82

1

2

J83

1

2

D V N 2 G 1 e d u e l r b 1 2

V 2 1

D N G

V 2 1

e u l b 1

d e r 2

e u l b 1

d e r 2

1

2

1

2

J84

J85

J89 1 red

3 red 4 black

J86

12V

1

2 black

12&5V board BA33-30-35080

12V

12V

2

COOLER

3

12V

4

GND

Reagent refrigeration board BA30-30-06312

GND

COOLER

GNDFAN 12FAN

J74

1

2

w o l l e y 1

e u l b 2

4 2 5 D 6 e 0 l - N G b a 0 2 C 0 3 A w B o l l e y 3 3

1

2

3

1

2

3

1

2

3

d e r 3

w o l l e y 1

e u l b 2

d e r 3

w o l l e y 1

e u l b 2

d e r 3

w o l l e y 1

e u l b 2

d e r 3

N A F

V 2 1

D N G

N A F

V 2 1

D N G

N A F

V 2 1

D N G

N A F

V 2 1

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

w o l l e y 3

e u l b 2

d e r 1

2

3

1

J73

3

2

1

J72

3

2

1

J71

3

2

1

J75

1

2

1

2

e u l b 1 5 2 5 6 e 0 l b D a 0 2 - N C 0 3 G A B

d e r 2

e u l b 1

d e r 2

V 2 1

D N G

V 2 1

d e r 1

e u l b 2

d e r 1

e u l b 2 2

1

J76

2

1

J77

1

2

e u l b 1

d e r 2

e u l b 2

d e r 1 2

1

J87

1

2

3

k c a l b 1

e t i h w 2

d e r 3

N A F

V 5

e t i h w 2

d e r 3

2

3

0 8 4 6 e 0 l - D b N a 0 2 - G C 0 3 A B k c a l b 1 1

J42 M37-M38: Fans on sides of lamp housing 2100-20-08114

M24-M27: Reaction temperature fan BA30-21-06530

A-5

Fan on rear side of lamp housing


Cable BA30-20-15308

4 yellow

P353

5

5 yellow

4

1

4

1 blue 5

2

6

3

6

3

2 blue

2

3 white

1

6 orange


r o t o m 2 g 5 n 0 5 i x 1 i 0 m 1 C 0 0 D 0 : 9 2 1 - M +

C31: Reagent probe

C32: Sample probe

E B D O N R G P k d c e a r l b 2 1 6 4 5 6 e 0 l b 0 a 2 C 0 3 A B k c a d l b e r 1 2

E B D O N R G P k d c a e r l b 2 1 7 4 5 6 e 0 l b a 0 2 C 0 3 A B k c a d l e r b 2 1

r e c u 1 g d 3 n s 6 i t n 6 a a e t r 0 h 0 e r e 1 r P t 0 : u a 0 r 3 3 e A C p B m e t

r 5 e 1 t 1 a e 5 1 h e r 0 P 1 : 0 9 3 2 A M B

1

J66

2

6 9 2 5 e 1 l b a 0 2 C 0 3 A B

k c a l b 1

d e r 2

1

2

J202

1

2

3

4

1

2

3

4

1

e g n a r o 2

w o l l e y 1 J201

1

n w o r b 3

e l p r u p 4

D N G A n e e r g 5

3

4

5

2

L E V E L _ P R k c a l b 7

V 2 1 d e r 8

6

7

8

2

3

4

2

3

4

D N G A n e e r g 1

O H P _ M A R _ P S e u l b 2

L E V E L _ P S k c a l b 3

V 2 1 d e r 4

1

2

3

4

1

2

3

4

1 n e e r 2 g 9 2 5 e 1 l b a 0 2 C 0 3 A B n e e r g 1

2 e u l b

3 e t i h w

4 d e r

e u l b 2

e t i h w 3

d e r 4

2

3

4

5 9 2 5 e 1 l b a 0 2 C 0 3 A B

O H P _ M A R _ P R e u l b 6

2

Sampel level detection board BA30-30-06304 J65

1 4 9 2 5 e 1 l b a 0 2 C 0 3 A B

1

J66

Reagent level detection board BA30-30-06304 J65

J200

Probes connection board BA30-30-15284

J206

J207

J205

J204

1

2

1

2

1

2

1

1 e u l b 3 0 6 3 e 6 l b a 0 2 C 4 3 A B e u l b 1

2 d e r


2 d e r

2 d e r

d e r 2

1 k c a l 0 b 9 2 5 e 1 l b a 0 2 C 0 3 A B k c a l b 2


2

5 4 J 1

2 2 J 1

d e r 2 2

4 2 J

1

d e r 3 2

3

4 3 J

1

J203 2

3

4

2 e u l b

3 e t i h w

4 d e r

e u l b 2

e t i h w 3

d e r 4

2

3

4

5 3 J

1


Power drive board BA34-30-63559

A-7


r o t o m 2 g 5 0 n i 5 x 1 i m 0 1 C 0 D 0 : 0 9 2 1 - M +

C31: Reagent probe

C32: Sample probe

E B D O N R G P k c d e a r l b 2 1 6 4 5 6 e 0 l b a 0 2 C 0 3 A B k c a d l b e r 1 2

E B D O N R G P k d c e a r l b 2 1 7 4 5 6 e 0 l b a 0 2 C 0 3 A B k c a d l e r b 2 1

r e c u 1 g d n s 3 i 6 t n 6 a a e t r 0 h 0 e r e r 1 P t 0 : u 3 0 a r 3 e A C p B m e t

r 5 e 1 t 1 a e 5 1 h e r 0 P 1 : 0 9 3 2 A M B

1

J66

2

6 9 2 5 e 1 l b a 0 2 C 0 3 A B

k c a l b 1

d e r 2

1

2

J202

1

2

3

4

1

2

3

4

1

e g n a r o 2

w o l l e y 1 J201

1

n w o r b 3

e l p r u p 4

D N G A n e e r g 5

3

4

5

2

2

L E V E L _ P R k c a l b 7

V 2 1 d e r 8

6

7

8

3

4

2

3

4

D N G A n e e r g 1

O H P _ M A R _ P S e u l b 2

L E V E L _ P S k c a l b 3

V 2 1 d e r 4

1

2

3

4

5 9 2 5 e 1 l b a 0 2 C 0 3 A B

O H P _ M A R _ P R e u l b 6

2

Sampel level detection board BA30-30-06304 J65

1 4 9 2 5 e 1 l b a 0 2 C 0 3 A B

1

J66

Reagent level detection board BA30-30-06304 J65

J200

Probes connection board BA30-30-15284

J206

J207

J205

J204

1

2

1

2

1

2

1


2 d e r


2 d e r

2 d e r

d e r 2

1 k c a l 0 b 9 2 5 1 e l b a 0 2 C 0 3 A B k c a l b 2


2

5 4 J 1

2 2 J 1

d e r 2

4 2 J

2

1

d e r 3 2

4 3 J

3

J203 2

3

4

2 e u l b

3 e t i h w

e u l b 2

e t i h w 3

d e r 4

2

3

4

1

4 d e r

1

2

3

1 n e e 2 r 9 g 2 5 e 1 l b 0 a 2 C 0 3 A B n e e r g 1

2 e u l b

3 e t i h w

4 d e r

e u l b 2

e t i h w 3

d e r 4

2

3

4

5 3 J

1

4



A-7


2 red Cable BA33-21-35151

1 blue 2 red

Cable BA33-21-35152

1 blue

J104

J3 4

MAGU+ MAGU-

3

MAGD+

2

MAGD-

1

Cable J106 BA30-20-06463 4 red 4 red 4 3 blue

3 blue 2 yellow

2 yellow

1 white

1 white

GND MAGD_PHO GND GND

7

3 5

9

2

1

+ D G A M

D G A M

J105

3

MAGU-

2

MAGD+

1

MAGD-

blue red blue

M2: Upper finger magnet BA30-21-06497

M1: Lower finger magnet BA30-21-06498

J101 VCC LOADX_PHO

4 3

GND

2

GND

1

4 red 3 white

Cable BA33-21-35153

2 black

red white black

1 green

C1: Manipulator horizontal position transducer transducer BA30-21-06495

green

J102 VCC LOADY_PHO

Manipulator connection board BA30-30-06316

4 3

GND

2

GND

1

4 red 3 white

Cable BA33-21-35154

2 black

red white black

1 green

C2: Manipulator vertical position transducer transducer BA30-21-06496

green

J108

J43 1

1 U G A M

MAGU+


URAM_PHO LOADX_PHO DRAM_PHO LOADY_PHO VCC MAGU_PHO

2

+ U G A M


red

2 4 6 8

1 2 3 4 5 6 7 8 9 10

Cable BA30-20-06486

1 2 3 4 5 6 7 8 9 10

J107 1 3 5 7 9

2 4 6 8 10

VCC


4


3

2

1

4 red

3

3 white

GND

2

2 blue

GND

1

1 black

MAGU_PHO

Cable BA33-20-35150

red white blue

C3: Upper electromagnet electromagnet transducer BA30-30-15060

black

J103 VCC MAGD_PHO O H P _ GND M A D D R N N GND D G G

O H P _ M A D D R N U N G G J110

4

J109

4

3

A-8

2

1

4 3 2 1

4 red 3 white 2 blue 1 black

Cable BA33-20-35149

red white blue black

C4: Lower electromagnet transducer BA30-30-15062



1 blue 2 red

Cable BA33-21-35152

1 blue

J104 Power drive board BA34-30-63559 J3

Cable J106 BA30-20-06463 4 red 4 red 4

4

MAGU+ MAGU-

3

MAGD+

2

MAGD-

1

3 blue

3 blue 2 yellow

2 yellow

1 white

1 white

3

MAGU-

2

MAGD+

1

MAGD-


7

3 5

M2: Upper finger magnet BA30-21-06497

blue red

M1: Lower finger magnet BA30-21-06498

blue

J101

2

1

+ D G A M

D G A M

J105

VCC

4 red

4

LOADX_PHO

3

GND

2

GND

1

Cable BA33-21-35153

3 white 2 black

red C1: Manipulator horizontal position transducer transducer BA30-21-06495

white black

1 green

green

J102 VCC

4 red

4

LOADY_PHO

white

2 black

2

C2: Manipulator vertical position transducer transducer BA30-21-06496

black

1 green

1

GND

red

Cable BA33-21-35154

3 white

3

GND

Manipulator connection board BA30-30-06316

green

J108

J43 1

1 + U U G G A A M M

MAGU+



2

red

Cable BA30-20-06486

1 2 3 4 5 6 7 8 9 10

2 4 6 8

9

1 2 3 4 5 6 7 8 9 10

J107 1 3 5 7 9

2 4 6 8 10

VCC

URAM_PHO LOADX_PHO DRAM_PHO LOADY_PHO VCC MAGU_PHO GND MAGD_PHO GND GND

4

3

2

4 red

3

3 white

GND

2

2 blue

GND

1

1 black

MAGU_PHO

red

Cable BA33-20-35150

C3: Upper electromagnet electromagnet transducer BA30-30-15060

white blue black

J103 4

VCC MAGD_PHO O H P _ GND M A D D R N N GND D G G

O H P _ M A D D R N N U G G J110

4

1

4

J109

3

2

3 2 1

4 red

red

Cable BA33-20-35149

3 white

C4: Lower electromagnet transducer BA30-30-15062

white

2 blue

blue

1 black

black

1

A-8


Cable BA30-20-06490

4 red 3 white

white

2 black

black

1 green


1 3

3

2

1

VCC

2 4

5

6

7

8

9

10

1 2 3 4 5 6 7 8 9 10

3

GND

2

GND

1

1 2 3 4 5 6 7 8 9 10

1

VCC PRESSURE_PHO 4 FRONT_PHO BUTTON_S MIDDLE_PHO 3 BACK_PHO VCC GND 2 MIDDLE_PHO GND 1 GND LOADE_PHO J94 GND GND VCC 4

2

3

4

5

6

7

8

9

10

3 white

2 black

GND

1

1 green

J95

DC+ 2

DC1

PRESSURE_PHO

3

GND

2

GND

1

DC+ DCJ97

2

1

J96 1 black

2 red

4


1 blue Cable BA30-20-06464

A-9

DCDC+

red white black

C10: No-cuvette transducer BA30-21-06489

green Cable BA30-20-06488

4 red

C9: Insufficient-cuvette Insufficient-cuvette transducer BA30-21-06492


2

VCC

black

1 green

GND

red white

2 black

4 red

C8: Cuvette-taking limit transducer BA30-21-06491


3 white

1

black

1 green

4 red

red white

2 black

3

2

Power drive board BA34-30-63559 DC+ 2 DC- 1

4 red 3 white

LOADE_PHO

J98

J19

Cable BA30-20-06491

J93

J99

Cable BA30-20-06485

4

BACK_PHO Feeder connection board BA30-30-06314

J32 PRESSURE_PHO FRONT_PHO BUTTON_S BACK_PHO VCC MIDDLE_PHO GND LOADE_PHO GND GND

4

C7: Cuvette-pushing limit transducer BA30-21-06490

green J92

J91

red

3 white 2 black 1 green

M5: Feeder motor BA30-21-06494

red white black green

C11: Pressure transducer BA30-21-06488


Cable BA30-20-06490

4 red 3 white

white

2 black

black

1 green 4

3

2

1

VCC BACK_PHO


Feeder connection board BA30-30-06314

J32 PRESSURE_PHO FRONT_PHO BUTTON_S BACK_PHO VCC MIDDLE_PHO GND LOADE_PHO GND GND

1 3

2 4

5

6

7

8

9

10

1 2 3 4 5 6 7 8 9 10

1 2 3 4 5 6 7 8 9 10

1

2

GND

1

VCC PRESSURE_PHO 4 FRONT_PHO BUTTON_S MIDDLE_PHO 3 BACK_PHO VCC GND 2 MIDDLE_PHO GND 1 GND LOADE_PHO J94 GND GND VCC 4

4

5

6

7

8

9

10

J98

3 white

2

GND

1

1 green

DC+ 2

DC1

4

PRESSURE_PHO

3

GND

2

GND

1

DC+ DCJ97

2

1

J96 1 black

2 red


1 blue Cable BA30-20-06464

A-9

DCDC+

red white black

C10: No-cuvette transducer BA30-21-06489


4 red

C9: Insufficient-cuvette Insufficient-cuvette transducer BA30-21-06492


GND

VCC

black

1 green

2 black

red white

2 black

4 red

C8: Cuvette-taking limit transducer BA30-21-06491


J95

1

black

1 green

4 red

red white

2 black

3 white

2

Power drive board BA34-30-63559 DC+ 2 DC- 1

4 red 3 white

3

LOADE_PHO

J19

3

Cable BA30-20-06491

J93 2

3

4

GND

J99

Cable BA30-20-06485

C7: Cuvette-pushing limit transducer BA30-21-06490

green J92

J91

red

3 white 2 black 1 green

M5: Feeder motor BA30-21-06494

red white black green

C11: Pressure transducer BA30-21-06488

Test Points of Boards

Ap A p p end en d i x B B.1

Test es t Poi Po i n ts o f B o ard ar d s

Test Points on A/D Conversi on Board

TP TP1

TOP/BOTTO TOP/BOTTOM M TOP

Descr ipt ion s The signal at 340nm

TP2

TOP

The signal at 405nm

TP3

TOP

The signal at 450nm

TP4

TOP

The signal at 510nm

TP5

TOP

The signal at 546nm

TP6

TOP

The signal at 578nm

TP7

TOP

The signal at 630nm

TP8

TOP

The signal at 670nm

TP9

TOP

The signal at 700nm

TP10

TOP

The signal of REF

TP11

TOP

The start signals of AD conversion

TP12

TOP

GND

TP13

TOP

The input analog signals of AD conversion

B.2

Test Points on Drive Board

TP

TOP/BOTTO TOP/BOTTOM M

Descr ipt ion s

TP1

TOP

Signal ground (SHIELD) from the main control board

TP2

TOP

5V and 24V ground (GND)

TP3

TOP

5V and 24V ground (GND)

TP4

TOP

12V ground (12VGND)

B.3

Test Points on Reagent Reagent Refri Refri geration Board

TP


Descr ipt ions io ns

TP1

TOP

The temperature switch signal (low)

TP2

TOP

The temperature switch signal (high)

TP3

TOP

Reference ground

TP4

TOP

The switch characteristic of Q1

TP5

TOP

The voltage of the temperature transducer

B.4

Test Points on Main Main Contro l Board

TP


Descr ipt ion s

TP1

BOTTOM&TOP

TxD of Sample Unit

B-1

Test Points of Boards TP


Descr ipt ion s

TP2

BOTTOM&TOP

RxD of Sample Unit

TP3

BOTTOM&TOP

ALE of Sample Unit

TP4

BOTTOM&TOP

TxD of photoelectric photoelectr ic unit

TP5

BOTTOM&TOP

RxD of photoelectric photoelectri c unit

TP6

BOTTOM&TOP

ALE of photoelectric photoelectr ic unit

TP7

BOTTOM&TOP

INT of SPI port

TP8

BOTTOM&TOP

RxD of Main unit

TP9

BOTTOM&TOP

TxD of Main unit

TP10

BOTTOM&TOP

ALE of Main unit

TP11

BOTTOM&TOP

Clock Output of Crystal 16MHZ

TP12

BOTTOM&TOP

TxD of loading/mixing loading/mix ing unit

TP13

BOTTOM&TOP

RxD of loading/mixing loading/mix ing unit

TP14

BOTTOM&TOP

ALE of loading/mixing loading/mix ing unit

TP15

BOTTOM&TOP

GND

TP16

BOTTOM&TOP

VDD 3.3V power

TP17

BOTTOM&TOP

VEE 1.5V power

TP18

BOTTOM&TOP

VTTP +15V power

TP19

BOTTOM&TOP

VTTN -15V power

TP20

BOTTOM&TOP

GNDTT GND of

TP21

BOTTOM&TOP

VCC 5V Power

TP22

BOTTOM&TOP

VPP 12V power

TP23

BOTTOM&TOP

VCCA analog power of 5V

TP24

BOTTOM&TOP

AGND analog GND of 5V

TP25

BOTTOM&TOP

GND

TP26

BOTTOM&TOP

RxD of Sample Unit Extended COM for Bar Code Scanner

TP27

BOTTOM&TOP

TxD of Sample Unit Extended COM for Bar Code Scanner

TP28

BOTTOM&TOP

TxD of Reagent Unit Extended COM for Bar Code Scanner

TP29

BOTTOM&TOP

RxD of Main Unit Extended COM for ISE module

TP30

BOTTOM&TOP

RxD of Reagent Unit Extended COM for Bar Code Scanner

TP31

BOTTOM&TOP

TxD of Main Unit Extended COM for ISE module

TP32

BOTTOM&TOP

Clock Output of Crystal 10MHZ

TP33

BOTTOM&TOP

ALE of temperature unit

TP34

BOTTOM&TOP

TxD of temperature unit

TP35

BOTTOM&TOP

RxD of temperature unit

TP36

BOTTOM&TOP

RxD of Reagent unit

TP37

BOTTOM&TOP

TxD of Reagent unit

TP38

BOTTOM&TOP

ALE of Reagent unit

B-2

±15V


B.5

Test Points Poin ts on PFC PFC Board Bo ard

TP


Descr ipti ip tions ons

TP1

BOTTOM

The switch waveforms of Q3 and Q4

TP2

BOTTOM

The drive waveform of Q5

TP3

BOTTOM

The DC output (390V)

TP4

BOTTOM

The reference voltage of U2 (7.5V)

TP5

BOTTOM

The oscillation oscillat ion waveform of U2 (100KHz)

TP6

BOTTOM

The Vss supply (19V)

TP7

BOTTOM

The VDD supply (14V)

TP8

BOTTOM

The VPP supply (12V)

TP9

BOTTOM

The drive waveform of Q12 (85KHz)

TP10

BOTTOM

The switch waveform of Q12

TP11

BOTTOM

The current waveform of Q12

TP12

BOTTOM

The reference voltage of U8 (5V)

TP13

BOTTOM

The oscillation oscillat ion waveform of U8

TP14

BOTTOM

The 12V(4.5A) supply

B.6

Test Points Poin ts on 5V/1 5V/12V 2V Board Bo ard

TP


Descr ipti ip tions ons

TP1

BOTTOM


TP2

BOTTOM

Input side as reference ground

TP3

BOTTOM

The VDD supply (14V)

TP4

BOTTOM

The oscillation oscilla tion waveform of U301 (100KHz)

TP5

BOTTOM


TP6

BOTTOM

The switch drive waveform

TP7

BOTTOM

The switch waveform

TP8

BOTTOM

The 12V(10A) output

TP9

BOTTOM

The output control voltage of the board

TP10

BOTTOM

The 12V(4.7A) output

TP11

BOTTOM

The supply of FAN (12V)

TP12

BOTTOM

The 5V output of the board

TP13

BOTTOM

Output side as reference ground

TP14

BOTTOM

The switch waveform of U355 (72KHz)

TP15

BOTTOM

Short circuit with the output side reference ground and measure the OVP point of the two 12Vs

TP16

BOTTOM

Short circuit with the output side reference ground and measure the OVP point of the two 5V

B-3


B.7

Test Points Poin ts on 24V 24V Board Bo ard

TP


Descr ipt ion s

TP1

BOTTOM


TP2

BOTTOM

Input side as reference ground

TP3

BOTTOM

The switch waveform

TP4

BOTTOM

The switch drive waveform

TP5

BOTTOM

The current waveform of Q402

TP6

BOTTOM

The VCC supply (14V)

TP7

BOTTOM


TP8

BOTTOM

The oscillation waveform of U405 (100KHz)

TP9

BOTTOM

The power on/off

TP10

BOTTOM

The 24V output

TP11

BOTTOM

Output side as reference ground

TP12

BOTTOM

The voltage waveforms at the two ends of the rectifier rectifi er and fly-wheel diode

TP13

BOTTOM

Short circuit with the output side reference ground and measure the OVP point of the 24V

B-4

P/N: BA34-20-63690 (1.0)

BS-300 Service Manual

Recommend Documents