DRUG STUDY Cefuroxime

DRUG STUDY Name Generic Name: CEFUROXIME Brand Name: ZOLTAX Classification: ANTIBIOTIC Frequency: BID

Mechanism of Action Second-generation cephalosporin that inhibits cellwall synthesis, promoting osmotic instability; usually bactericidal.

Indication/Contraindication Indication/Contraindication Indication: Pharyngitis, tonsillitis, infections of the urinary and lower respiratory tracts, and skin and skin-structure infections caused by Streptococcus pneumoniae and S. pyogenes, Haemophillus influenzae, Staphylococcus aureus, Escherichia coli.

Dosage: 1 tab 500 mg

Body as a Whole: Thrombophlebitis (IV site); pain,burning, cellulitis( IM site);superinfections,positive Coombs'test. GI: Diarrhea, nausea, antibiotic-associated colitis.

Nursing Responsibility       Determine history of 

hypersensitivity reactions to cephalosphorins, penicillins and history of allergies particularly to drugs before therapy is initiated.       Report onselt of loose

Skin: Rash, pruritus, urticaria.

stools       Absorption of 

Contraindicated: Route: PO

Side Effects

* Contraindicated in patients hypersensitive to drug. * Use cautiously in patients hypersensitive to penicillin because of possibility of crosssensitivity with other betalactam antibiotics. * Use with caution in breastfeeding women and in patients with history of colitis or renal sufficiency.

Urogenital: Increased serum cretonne and an d BUN,decr decrea ease sed d creat cre atin inin ine e clearance

cefuroxime is enhanced by food.       Notify prescriber

about rashes or superinfections

DRUG STUDY Name Generic Name: BISACODYL Brand Name:

Classification: CATHARTICS AND LAXATIVES Frequency: OD HS Dosage: 1 tab 10 mg Route: PO

Mechanism of Action Bisacodyl works by stimulating enteric nerves to cause colonic mass movements. It is also a contact laxative; it increases fluid and NaCl secretion. Action of bisacodyl on small intestine is negligible; stimulant laxatives mainly promote evacuation of  the colon.

Indication/Contraindication

Indication:       Constipation       Evacuation of bowel

before radiologic studies or surgery

Containdicated:

Side Effects       Abdominal cramps

(colic, cramps)       Nausea       Diarrhea       Hypokalemia       Muscle weakness

Nursing Responsibility Assess bowel sounds Do not give if patient ahs abdominal pain Teach the patient:       short-term therapy

only       Acute surgical

      increase fluid intake

abdomen or intestinal obstruction       severe dehydration       fecal impaction       chronic use.

      bulk up the diet       normal bowel habits

may vary from 3 times/day to 3 times/week