Answer Key

Answer Key Question 1: (see full question)

You Yo u selected:

A nurse is explain explaining ing to a patient about about the need to administer a loading dose of a drug. Which of the following statements best reflects the reason for administering the loading dose? "We want to mae sure that the drug becomes effecti!e faster."

Correct

Explanation:

A loading dose is recommend recommended ed for use use with drugs drugs that may tae a prolonged period to reach critical concentration so that the effects can be obtained more quicly. i#e is unrelated to the use of a loading dose. $!aluating the body%s response is not an indication for using a loading dose. &uration of action is not an indication for using a loading dose. (less ( less))

Reference:

Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. 5+655.

Question 2:

A patient is recei!ing recei!ing 152 mg of a drug drug that has has a half6life half6life of 31 hours. ow much drug would remain after 78 hours?

(see full question)

You Yo u selected:

73.15 mg

Correct

Explanation:

Reference:

Question 3: (see full question)

You Yo u selected: Incorrect

9his amount of drug is present after 78 hours. 9his amount of drug would be present after 31 hours. 9his amount of drug would be present after 1+ hours. 9his amount of drug would b... (more ( more)) Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. When a drug is discontinued' what percentage of that drug will remain in the body after three half6li!es? 15:

Correct response:

31.5:

Explanation:

$ach half6life remo!es 52: of the drug stored in the body. ence' after one half6life' the percentage of drug in the body would be 52:. After two half6li!es' the percentage of drug in the body would be half of 52:' which is 15:. 4onsequently' after three half6li!es' the percentage of drug would be 31.5:. (less ( less))

Reference:


You Yo u selected:

Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. ;our patient is taing low dose aspirin daily for their heart. ;ou now that the patient is not recei!ing all the dosage of the aspirin that is being ingested. 9his occurs because of what? 0i!er metabolism

Incorrect

Correct response:

Explanation:

A large percentag percentage e of an oral oral dose is destroyed destroyed when when it reaches the li!er and ne!er reaches the tissues. 9his phenomenon is nown as the first6pass effect. 9herefore =ptions A' 4' ... (more ( more))

Reference:

Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +>.

Question 5:

9he nursing students are learning about the half6life of drugs. A student ass the instructor to explain half6life. What would be the instructor%s best response?

(see full question)

You Yo u selected:

alf6life of a drug is the time it taes for the drug to reach  of its% potential pea le!el in the body.

Incorrect

Correct response:

alf6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed.

Explanation:

9he half6life of a drug is the time it taes for the amount of

drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. 9herefore =ptions @' 4' and & are ... (more more)) Reference:


You Yo u selected:

Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. &rugs do not metaboli#e the same in all people. n which of the following patients would a nurse expect to see an alteration in drug metabolism? A 526yea 526year6old r6old male with cirrhosis cirrhosis of the li!er

Correct

Explanation:

Reference:


You Yo u selected:

9he li!er is the most important site of drug metabolism. f the li!er is not functioning effecti!ely lie in patients with cirrhosis' drugs will not be metaboli#ed normally and tox... (more more)) Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in th Nursing ' + ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8. 9he nurse is explaining the pharmacoinetics of a drug being administered to a client. What is meant by the term "pharmaoinetics?" Actions of of drugs

Correct

Explanation:

Reference:

,harmacoinetics refers to the actions of drugs. 9he route of administration refers to the route or method by which a medication is administered. 9reatment of o!erdoses and dosages... (more ( more)) Aschenbrenner'' &..' Aschenbrenner &..'  enab enable' le' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1.


You selected:

9he nurse is preparing to administer a prescribed drug to a patient with a history of renal disease. 9he nurse expects a reduction in dosage based on the understanding that which of the following might be altered? Betabolism

Incorrect

Correct response:

$xcretion

Explanation:

f the idneys are not functioning properly' a drug may not be excreted properly and could accumulate in the body. Betabolism may be altered if the patient has li!er disease.... (more)

Reference:

Question 9:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +C. Drine acidity can play an important role in drug excretion.

(see full question)

You selected:

9rue

Correct

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 52.

Question 1:

9he patient is a six6year6old who is taing 315 mg of Amoxicillin e!ery 8 hours. Assuming that the half6life of Amoxicillin is 7 hours' how much Amoxicillin would be in the child%s body at the time of the next administration of the drug?

(see full question)

You selected:

73.15 mg

Correct

Explanation:

Reference:

9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. =ption A would occur at 7 hours af... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in

Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53.


You selected:

When drugs are bound to proteins in the blood they can be transported to different areas of the body. 9he protein6drug complex is relati!ely large and cannot enter into capillaries and into tissues to react. What must occur for drugs to do their Eob in the body? 9he drug must be freed from the protein binding site

Correct

Explanation:

Reference:


You selected:

Bost drugs are bound to some extent to proteins in the blood to be carried into circulation. 9he proteinFdrug complex is relati!ely large and cannot ente... ( more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. ++. &rugs that are highly lipid soluble are more liely to pass through the blood6brain barrier and reach the central ner!ous system. 9rue

Correct

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8. =nly drugs that are lipid soluble or ha!e a transport system ha!e the ability to4ross the blood6brain barrier.

Correct

Explanation:

9he blood6brain barrier is composed of tight walls' limiting mo!ement of drug molecules. 9his barrier maes drug therapy for the 4G difficult because drug molecules cannot pass th... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8.

Question 14:

A pharmacology student ass the instructor what an accurate description of a drug agonist is. What would be the instructor%s best response?

(see full question)

You selected:

A drug that interacts directly with receptor sites to cause the same acti!ity that a natural chemical would cause at that site

Correct

Explanation:

Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters' hormones' or other substances found in the body. Gon6 competiti!e antago... (more)

Reference:


Question 15:

A client older than 85 years is more liely to experience drug reaction than a client younger than 52 years. Which of the following factors accounts for this de!elopmental !ariation?

(see full question)

You selected:

Age6related physiologic changes

Correct

Explanation:

Reference:

n older adults (85 years and older)' physiologic changes may alter all pharmacoinetic processes. Although drugs crossing the bloodFbrain barrier affect drug reaction' this ... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmcodynamics' p. +H.


You selected:

Which of the following represents a pharmacoinetic phase? elect all that apply. I Betabolism I $xcretion I &istribution I Absorption

Correct

Explanation:

9he pharmacoinetic phases are absorption' distribution' metabolism' and excretion. 9he acronym A.&.B.$. is a helpful way to remember to pharmacoinetic phases.... (more)

Reference:


Question 17:

A nurse is to administer a drug that is loosely bound to protein. 9he nurse understands that this would mean which of the following?

(see full question)

You selected:

9he drug will lead to toxicity with other drugs.

Incorrect

Correct response:

9he drug will ha!e a short duration of action.

Explanation:

&rugs that are loosely bound to protein act !ery quicly and are excreted !ery quicly. &rugs that are tightly bound to protein are released !ery slowly. &rugs that are tightly bou... (more)

Reference:


You selected: Correct

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. ++6+8. ,harmacotherapeutics is the achie!ement of the desired therapeutic goal of drug therapy. What standard does the <&A apply to a drug for appro!al? 9he drug has to be statistically significantly more effecti!e than placebo.

Explanation:

f the clinical studies indicate that the effect a drug has on the desired treatment outcome is statistically significantly better than that achie!ed with a placebo (an inacti!e su... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1.

Question 19:

A drug with a half6life of + hours is administered at a dosage of 322 mg. ow much of the drug will be in the patient%s system > hours after administration?

(see full question)

You selected:

15 mg

Correct

Explanation:

Reference:

Question 2: (see full question)

You selected:

9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. =ption A would occur 1 hours after... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. 9he route medication must be gi!en to achie!e 322: bioa!ailability is gi!en.

Correct

Explanation:

Reference:

&rugs gi!en !ia the oral route' B' and sub q routes are !irtually always less than 322: a!ailable because some of the drug is absorbed in the J or li!er before reaching systemic ... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +7.

Answer Key Question 1:

What does the lipid solubility of the drug influence?

(see full question)

You selected:

Absorption of the drug

Incorrect

Correct response:

&istribution of the drug

Explanation:

As with absorption' factors that can affect distribution include the drug%s lipid solubility and ioni#ation and the perfusion of the reacti!e tissue. 9he lipid solubility of a drug... (more)

Reference:



You selected:

Which of the following is a ey process with drug excretion? Acti!e transport

Correct

Explanation:

Although acti!e transport may be in!ol!ed with absorption' it is a !ery important process in drug excretion in the idney. ,assi!e diffusion is the maEor process through which drug... (more)

Reference:



You selected:

What types of medication can pass through the bloodF brain barrier or the placenta? (elect all that apply.) I Water6soluble medications I oni#ed medications I 0ipophilic medications I Bedications unbound to protein

Incorrect

Correct response:

I Water6soluble medications I 0ipophilic medications I Bedications unbound to protein

Explanation:

9he bloodFbrain barrier and the placental barrier are protecti!e mechanisms in the body that protect the brain or fetus from toxins. n order for a medication to pass throug... (more)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +8. Which factors will decrease the rate of drug absorption? elect all that apply. I A disease that alters the stomach and small intestine lining

Incorrect

Correct response:

I igher drug concentration in the circulatory system I &rug gi!en by a subcutaneous route !ersus an intramuscular route I A disease that alters the stomach and small intestine lining

Explanation:

ncreased blood flow will increase the rate of absorption' but if there is a higher concentration of the drug already in the blood' then the drug will not be absorbed as quicly. &... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +7.


You selected:

Which drug would most liely induce the effects of the cytochrome ,+52 en#yme system? Ketocona#ole

Incorrect

Correct response:

Gicotine

Explanation:

Gicotine' alcohol' and glucorticoids such as cortisone induce the effects of the ,+52 en#yme system. Ketocona#ole' quinidine' and mexilitene inhibit the effects.... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' ,harmacodynamics' p. +H. Karch' A.B. .

Question 6:

A method that describes the process of absorption' distribution' and elimination of a drug in the body is nown as-

(see full question)

You selected:

,harmacoinetics.

Correct

Explanation:

oute of administration is the way in which the drug is introduced. ystemic drug effects are effects on body cells distant from the site of administration. &rug distribution in!ol... (more)

Reference:


Question 7:

A patient presents to the emergency department with a drug le!el of 52 units/m0. 9he half6life of this drug is 3 hour. With this drug' concentrations abo!e 15 units/m0 are considered toxic and no more drug is gi!en. ow long will it tae for the blood le!el to reach the non6toxic range?

(see full question)

You selected:

3 hour

Correct

Explanation:

Reference:


You selected:

alf6life is the time required for the serum concentration of a drug to decrease by 52:. After 3 hour' the serum concentration would be 15 units/m0 (52/1). After 1 hours the serum ... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53.
Correct

Explanation:

9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. At a dose of 522 mg =ption A would... (more)

Reference:


Question 9:

A nurse is administering digoxin to one of their patients. When administering a drug the nurse needs to consider the phases of what so that the drug they are administering can be made as effecti!e as possible?

(see full question)

You selected:

,harmacotherapeutics

Incorrect

Correct response:

,harmacoinetics

Explanation:

When administering a drug' the nurse needs to consider the phases of pharmacoinetics so that the drug regimen can be made as effecti!e as possible. ,harmacogenomics is the area of... ( more)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +1. 9he patient has a diagnosis of Bultiple clerosis and is taing the beta seron drug ebiff. 9he patient taes this drug by sub6q inEection 7 times a wee. 9he dosage is ++ mcg per inEection. f the patient taes an inEection on Bonday' how much of the drug would still be in the patient%s system when they tae their next inEection on Wednesday assuming the half6life of the drug is 1+ hours? 33 mcg

Correct

Explanation:

Reference:


You selected:

9he half6life of a drug is the time it taes for the amount of drug in the body to decrease to one6half of the pea le!el it pre!iously achie!ed. =ption A would occur 1+ hours afte... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 53. &rugs are chemicals that alter basic processes in body cells. 9hat means that&rugs can stimulate or inhibit normal cellular functionsL they cannot add functions.

Correct

Explanation:

Reference:

&osage form is a consideration in effecti!eness but not a maEor factor. &rugs are gi!en for systemic effects' and therapeutic le!els are dependant upon multiple factors.... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. 51.

Question 12:

Which drug would be considered an agonist?

(see full question)

You selected:

nsulin

Correct

Explanation:

nsulin is considered an agonist because it reacts with specific receptor sites to change the cell membrane permeability' interacting directly with the receptor sites to cause the ... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +,harmacotherapeutics' ,harmacoinetics' ,harmacodynamics' p. +H. Karch' A.B.
Question 13:

A nurse is caring for a patient who has been recei!ing a drug by the intramuscular (B) route. 9he physician writes discharge orders' which include an order for the drug to be gi!en orally. 9he nurse notices that the oral dosage is considerably higher than the parenteral dose. What does the nurse understand this is due to?

(see full question)

You selected:

Correct

Explanation:

Reference:

Question 14:

9he first6pass effect in!ol!es drugs that are absorbed from the small intestine directly into the portal !enous system' which deli!ers the drug molecules to the li!er. =nce in the... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +>. What influences drug absorption?

(see full question)

You selected:

oute of administration

Correct

Explanation:

&rug absorption is influenced by the route of

administration. ome drugs are not taen with fluid' e.g.' parenteral drugs' therefore =ption A is incorrect. 9he route of excretion d... (more) Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +7. 9here are many en#yme systems in the body. What is disrupted if a single step in any en#yme system is bloced? 4ell function

Correct

Explanation:

f a single step in one of the many en#yme systems is bloced' normal cell function is disrupted. 9herefore =ptions A' @' and 4 are incorrect.... ( more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. +>6+C.

Question 16:

A nurse would expect a drug to tae the longest to be absorbed if gi!en by which route?

(see full question)

You selected:

=ral

Correct

Explanation:

Reference:


Jenerally' drugs gi!en by the oral route are absorbed more slowly than those gi!en parenterally. Jenerally' parenterally administered drugs are absorbed more quicly than oral drug... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +7. ;ou are caring for a patient who is recei!ing Jentamycin'

152 mg and &iflucan' 522 mg at the same time. As the nurse you would now that if these two drugs competed with each other for protein binding sites what would this do? You selected:

Alter the effecti!eness of the drugs

Correct

Explanation:

Reference:

Question 18:

ome drugs compete with each other for protein binding sites' altering effecti!eness or causing toxicity when the two drugs are gi!en together. Gothing in the scenario would indica... (more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. +56+8. Bost oral drugs are best taen on an empty stomach.

(see full question)

You selected:

Incorrect

Correct response: Reference:

Question 19:

9rue Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. +7' ++. =ne function of metabolism is to-

(see full question)

You selected:

ncrease the rate of metabolism for endogenous steroidal hormones.

Incorrect

Correct response:

4on!ert fat6soluble drugs into water6soluble metabolites.

Explanation:

Bost drugs are lipid soluble' which aids mo!ement across cell membranesL howe!er' idneys can only excrete water6 soluble substances. 9herefore' metabolism of the drug includes con!... (more)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer

ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' pp. +86+H. Question 2: (see full question)

You selected:

A patient who is 8 feet tall and weighs 1>2 pounds will require which of the following doses? igher dose than a patient who weighs 3>2 pounds

Correct

Explanation:

Reference:


You selected:

n general' people hea!ier than a!erage may need larger doses' pro!ided their renal' hepatic' and cardio!ascular functions are adequate.... ( more) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +' ,harmacotherapeutics' ,harmacoinetics' and ,harmacodynamics' p. +H.

Which of the following is true of the hormone !asopressin? elect all that applyI asopressin regulates the reabsorption of water from the idney. I asopressin is secreted when body fluids must be conser!ed.

Correct

Explanation:

Reference:

9he following is true of the hormone !asopressin- is secreted by the posterior pituitary gland' is secreted when body fluids must be conser!ed' exhibits its greatest acti!ity on the renal tubular epithelium' regulates the reabsorption of water from the idney' and is used to treat diabetes insipidus. (less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 52&rugs Affecting ,ituitary' 9hyroid' ,arathyroid' and ypothalamic H.


You selected:

A client who is on estrogen therapy calls the clinic and tells the nurse that she is experiencing sudden' sharp chest pain. 9he nurse tells the client to go to the emergency department immediately' because the nurse suspects what ad!erse reaction related to estrogen therapy? ,ulmonary embolism

Correct

Explanation:

Reference:


You selected:

udden' sharp chest pain that may or may not include hemoptysis is a sign of pulmonary embolism. t may begin as a deep !ein thrombosis but the symptoms that the client describes are related to the lungs. @reast tenderness and seletal pain do not indicate a !isit to the emergency department. (less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 51&rugs Affecting WomenMs ealth and exuality' p. 3377.

Which of the following needs to be used in a child prior to the closure of the bone epiphyses in order to exert its effects? (4hoose one) omatropin

Correct

Explanation:

omatropin needs to be used in a child prior to the closure of the bone epiphyses in order to exert its effects. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 52&rugs Affecting ,ituitary' 9hyroid' ,arathyroid' and ypothalamic
Question 15:

A woman has been prescribed 4limara' a transdermal estradiol patch. Which of the following should she be instructed regarding the administration?

(see full question)

You selected: Correct

A!oid prolonged sun exposure at the patch site due to increased plasma concentrations.

Explanation:

9he total amount of drug absorbed and the resulting plasma drug concentrations from transdermal estrogen can increase during exposure to heat' so patients should be ad!ised to a!oid prolonged sun exposure in the area of the patch. 9he application of heat at the patch site will increase effecti!eness. 9he medication%s exposure to sunlight will not increase the ris of breast cancer. 9he medication%s exposure to cold will not change its effecti!eness. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 51&rugs Affecting Women%s ealth and exuality' p. 3375.

Question 16:

A 736year6old pregnant woman has been prescribed administration of a tocolytic drug. &uring which period is a tocolytic drug usually administered?

(see full question)

You selected:

,re6term labor

Correct

Explanation:

&rugs used to pre!ent uterine contractions are called tocolytics. 9hey are useful in the management of pre6term labor. 9hese drugs will decrease uterine acti!ity and prolong the pregnancy to allow the fetus to de!elop more fully' thereby increasing the chance of neonatal sur!i!al. =xytocic drugs are used antepartum (before birth of the neonate) to induce uterine contractions and initiate or augment labor. n the postpartum period and during the second stage of normal labor' the tocolytics are not of any importance. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 57' &rugs Affecting Dterine Botility' p. 3381.

Question 17:

A patient you are caring for has both warfarin and testosterone prescribed for separate disease processes. ;ou now that androgens may increase the effects of warfarin by what method of action?

(see full question)

You selected:

peeding up their metabolism

Incorrect

Correct response: Explanation:

lowing their metabolism Androgens may increase effects of cyclosporine and warfarin' apparently by slowing their metabolism and

increasing their concentrations in the blood. 9herefore =ptions 4 and & are incorrect. ( less) Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 53&rugs Affecting Ben%s ealth and exuality' p. 3337.

9he labor and deli!ery nurse administers ergono!ine to a patient after delie!ery of the placenta. 9he nurse does this9o pre!ent postpartum hemorrhage

Correct

Explanation:

Reference:


You selected:

Dterine stimulants increase the strength' duration' and frequency of uterine contractions and decrease the incidence of uterine bleeding. 9hey are gi!en after the deli!ery of the placenta and are used to pre!ent postpartum and postabortal hemorrhage caused by uterine atony. (less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 57' &rugs Affecting Dterine Botility' p. 335H. ;ou are caring for a client with cerebral edema caused by trauma. Which of the following medications would you anticipate being administered? &examethasone

Correct

Explanation:

&examethasone is considered the corticosteroid of choice for cerebral edema associated with brain tumors' craniotomy' or head inEury because dexamethasone is thought to penetrate the bloodFbrain barrier more readily and achie!e higher concentrations in cerebrospinal fluids and tissues. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter +>&rugs Affecting 4orticosteroid 0e!els' p. 3217.

Question 1:

A patient%s medication regimen for treatment of anxiety has been changed from a ben#odia#epine to buspirone

(see full question)

(@upar). 9he patient ass the nurse what maes this medication safer than the ben#odia#epine he has taen. What is the nurse%s best response? You selected:

Nt will not produce sedation lie ben#odia#epines.O

Correct

Explanation:

@uspirone will not produce sedation. 4ompared with the ben#odia#epines' buspirone (@upar) lacs muscle relaxant and anticon!ulsant effectsL does not cause sedation or physical or psychological dependenceL does not increase the 4G depression of alcohol and other drugsL and is not a controlled substance. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 171.

Question 3:

A H5 year old patient is brought to the emergency department by his family. 9he family relates that the patient is complaining of confusion' sei#ures and abnormal perception of mo!ement. When the nurse loos at the medication that the family has brought to the $& the nurse disco!ers that twice the number of tablets are missing from the !ial as the orders call for. What should the nurse suspect is wrong with this patient?

(see full question)

You selected:

@en#odiapene toxicity

Correct

Explanation:

Reference:

4ommon manifestations include increased anxiety' psychomotor agitation' insomnia' irritability' headache' tremor' and palpitations. 0ess common but more serious manifestations include confusion' abnormal perception of mo!ement' depersonali#ation' psychosis' and sei#ures. 9he scenario does not describe option @' 4 or & ( less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 11H.

hypnotic. 9ria#olam is a ben#odia#epine used as a hypnotic. ,rometha#ine is an antihistamine with sedati!e effects. ( less)


You selected:

A patient undergoing treatment with barbiturates is showing symptoms of barbiturate toxicity. Which of the following inter!entions should the nurse perform? ,ro!ide respiratory assistance

Correct

Explanation:

9he nurse must pro!ide respiratory assistance to the patient showing symptoms of barbiturate toxicity. ,ro!iding assistance with mo!ement' supporti!e care' and a safe en!ironment a... (more)

Reference:


Question 8:

A nurse is caring for a C6year6old patient and has recei!ed an order for dia#epam (alium) 32 mg ,= q.i.d. Which of the following should be the nurse%s initial action?

(see full question)

You selected:

4all the physician and question the order

Correct

Explanation:

9he first action of the nurse would be to call the physician and question the order. 9he normal dosage for a pediatric patient is 3 to 1.5 mg ,= t.i.d. or q.i.d. 9his would be an unsafe dose for this patient. f the dosage was changed and the correct amount administered' the nurse would order the medication from the pharmacy if necessary and determine what time to start the medication. he would then wash her hands in preparation of administering the medication. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 11C.

Question 9:

A patient who suffers from J$& and di!erticulosis has

(see full question)

You selected:

Eust been admitted to a medical floor. 9he admitting physician orders cimetadine and a sedati!e to calm the patient. About what should the nurse be concerned? ncreased sedati!e effect

Correct

Explanation:

An increased sedati!e effect may occur when a sedati!e is gi!en with cimetidine for gastric upset. 9he other options do not play a role in pro!iding the best care for the patient. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 17+.

$B depri!ation can lead to serious psychological problems' including psychosis.


You selected:

Which of the following is defined as a drug that induces drowsiness? (4hoose one) edati!e

Incorrect

Correct response:

ypnotic

Explanation:

A hypnotic is defined as a drug that induces drowsiness.

Reference:


Question 18: !see full "uestion# You selected:

Which action would be least appropriate for the nurse to do after administering an anxiolytic to a patient? &im the lights

$ncorrect Correct response:

a!ing the patient wal to the bathroom

Explanation:

a!ing the patient wal to the bathroom would be appropriate before administering the drug to reduce the patient%s ris for inEury. aising the side rails would be appropriate after administering an anxiolytic. ,lacing the call light within reach would be appropriate after administering an anxiolytic. &imming the lights would be appropriate after administering an anxiolytic. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in

Gursing' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 11H.


You selected:

Bs. Bole' a 856year6old woman with a history of chronic insomnia' is being seen in the physician office for follow6up care. 9he physician has ased you to de!elop a plan of care with Bs. Bole to impro!e her sleep. n addition to drug therapy' what would you recommend as part of the patient%s plan of care? Ad!ise the patient to a!oid food after 8-22 p.m.

Incorrect


Ad!ise the patient to practice relaxation techniques. n addition to the drug therapy' patients suffering from chronic insomnia may also need to apply beha!ioral techniques' such as relaxation therapy. elaxation techniques such as progressi!e relaxation and rhythmic breathing allow the muscles to relax and the mind to stop "racing'" thereby allowing natural sleep to occur. moing cigarettes before bedtime and taing long naps in the afternoon are some of the beha!iors associated with chronic insomnia. t is not necessary to a!oid all food in the e!ening. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35&rugs elie!ing Anxiety and ,roducing leep' p. 115.

Question 2: !see full "uestion#

A patient is admitted to a local health care facility for chronic insomnia. 9he physician prescribes es#opiclone. What should the nurse teach the patient when administering es#opiclone?

You selected:

A!oid drining alcohol

Correct Explanation:

Reference:

9he nurse should instruct the patient to a!oid alcohol during the period of es#opiclone therapy as alcohol interacts with es#opiclone to cause 4G depression. trenuous wor' use of tobacco' and exposure to sunlight do not cause any ad!erse reactions. ( less) Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35'

&rugs elie!ing Anxiety and ,romoting leep' p. 177.


You selected:

9he daughter of an older adult client ass the nurse if her father should be aware of any special precautions while taing lora#epam (Ati!an). What is the nurseMs best response? Bonitor for increased signs of confusion or forgetfulness.

Correct

Explanation:

ecent studies lin the chronic use of ben#odia#epines by those o!er 85 years of age to a greater chance of de!eloping dementia. Antianxiety drugs are not nown to cause idney or li!er damage but should be used cautiously in elderly clients' and in clients with impaired li!er function or impaired idney function. Antianxiety drugs more liely can cause muscle relaxation than rigidity. A symptom of withdrawal from antianxiety drugs is muscle tension. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35&rugs elie!ing Anxiety and ,romoting leep' p. 11H.

Question 2:

A patient suffers from generali#ed anxiety disorder. 9he patient suffers an acute episode of anxiety. @uspirone (@upar) is nown to be superior to ben#odia#epines. Why is the administration of buspirone (@upar) not recommended for this patient?

(see full question)

You selected:

t taes 1F+ wees to wor.

Correct

Explanation:

Reference:

@uspirone (@upar) has a delayed onset of action for up to 1F+ wees. 9hus' buspirone is not useful for acute episodes of anxiety and it may be difficult to persuade some patients to tae the drug long enough to be effecti!e. @uspirone (@upar) will not cause nausea and !omiting. 9he administration of this medication orally has no effect on the generali#ed anxiety disorder. exual dysfunction is not an ad!erse effect of buspirone. ( less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35'

&rugs elie!ing Anxiety and ,romoting leep' p. 171.

@en#odia#epines are classified in pregnancy category P and their use is contraindicated in pregnancy. ( less)

ydroxy#ine (istaril) is administered in the preoperati!e stage to decrease anxiety' nausea' and !omiting. ydroxy#ine (istaril) is not gi!en preoperati!ely to decrease oral secretions. ydroxy#ine (istaril) will not cause hypotension. ydroxy#ine (istaril) will not cause confusion. (less) Question 7: (see full question)

You selected:

When monitoring a patient recei!ing escitalopram for therapeutic effecti!eness' the nurse would eep in mind that full effect may tae up to how long? 1 wees

Incorrect

Correct response:

+ wees

Explanation:

t may tae up to + wees before the full effect of a  such as escitalopram is noted.

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 38' &rugs 9reating Bood &isorders' p. 1+7.

Question 8: !see full "uestion#

A patient is recei!ing lithium carbonate for treatment of bipolar disorder. Which of the following statements should be included in discharge education for this patient?

You selected:

"&o not dri!e while on this medication."


"Keep your scheduled appointments for measurement of lithium le!els."

Explanation:

erum lithium concentrations should be monitored frequently because they !ary widely among patients taing similar doses and because of the narrow range between therapeutic and toxic le!els. ( less)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 38- &rugs 9reating Bood &isorders' pp. 188618>.

A patient arri!es at the $ after attempting suicide by taing an entire bottle of dia#epam. Which of the following drugs will the nurse most liely administer?
Correct

Explanation:

Reference:


You selected:

. 9erry' age +8' has a history of bipolar disorder and has been taing lithium for the past 35 years. e recently began showing signs of low thyroid function and changes in his urinary output. Which ad!erse effect could be affecting 9erry%s idneys? 0ithium causes a decrease in the le!els of antidiuretic hormones.


0ithium impairs the ability of the idneys to concentrate urine.

Explanation:

0ong6term lithium therapy (exceeding 32 years) commonly impairs the ability of the idneys to concentrate urine' although this effect is not associated with a reduced glomerular filtration rate or with renal insufficiency. 0ow thyroid function can also occur in patients recei!ing long6 term lithium therapy. (less)

Reference:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphia- Wolters Kluwer

ealth/0ippincott Williams  Wilins' 1231' 4hapter 38&rugs 9reating Bood &isorders' p. 188. Question 17: !see full "uestion#

You selected:

A nurse is caring for a patient who has been administered a barbiturate. Which of the following are symptoms of barbiturate toxicity that the nurse must monitor the patient for? estlessness


ypotension

Explanation:

9he nurse must monitor the patient for hypotension' which is one of the symptoms of barbiturate toxicity. estlessness' euphoria' and confusion are withdrawal symptoms seen in the use of sedati!es and hypnotics. (less)

Reference:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 35' &rugs elie!ing Anxiety and ,romoting leep' p. 175.

Antidepressant therapy may be indicated if depressi!e symptoms persist at least 1 wees' impair social relationships or wor performance' and occur independently of life e!ents.


You selected:

9he mother of a child newly diagnosed with resistant epilepsy ass the nurse why two A$&s ha!e been prescribed for her daughter. What would be the nurse%s best answer? &ecreased ris of side effects

Incorrect

Correct response:

9o minimi#e sei#ures in resistant epilepsy

Explanation:

When monotherapy is ineffecti!e' a second' and sometimes a third' drug may be added. t does not decrease o!erall cost or reduce the ris of side effects or increase mo!ement of sodium ions into the cell. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 737.


You selected:

9he mother of a child newly diagnosed with resistant epilepsy ass the nurse why two A$&s ha!e been prescribed for her daughter. What would be the nurse%s best answer? &ecreased ris of side effects

Incorrect

Correct response:

9o minimi#e sei#ures in resistant epilepsy

Explanation:

When monotherapy is ineffecti!e' a second' and sometimes a third' drug may be added. t does not decrease o!erall cost or reduce the ris of side effects or increase mo!ement of sodium ions into the cell. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 737

Question 4:

A client tells the nurse he is going to stop taing his medication because he is always ha!ing fine tremors and slurred speech. 9hese reactions are pre!enting him from teaching art classes lie he used to do. 9he nurse nows that which of the following could help him?

(see full question)

You selected:

I e could tell his doctor that the antipsychotics are not woring and he needs a larger dose' or another medication added. I e could tal with his doctor and as to ha!e his medication dosage decreased' or change his medication to a second6generation antipsychotic.

Incorrect

Correct response:

Explanation:

I e could tal with his doctor and as to ha!e his medication dosage decreased' or change his medication to a second6generation antipsychotic.
medications. 9he symptoms are managed' so by stopping the drug the client is at ris of showing all the symptoms of schi#ophrenia. (less) Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3H&rugs 9reating ,sychotic &isorders and &ementia' p. 1>8.

Question 4:

A client tells the nurse he is going to stop taing his medication because he is always ha!ing fine tremors and slurred speech. 9hese reactions are pre!enting him from teaching art classes lie he used to do. 9he nurse nows that which of the following could help him?

(see full question)

You selected:

I e could tell his doctor that the antipsychotics are not woring and he needs a larger dose' or another medication added. I e could tal with his doctor and as to ha!e his medication dosage decreased' or change his medication to a second6generation antipsychotic.

Incorrect

Correct response:

I e could tal with his doctor and as to ha!e his medication dosage decreased' or change his medication to a second6generation antipsychotic.

Explanation:

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3H&rugs 9reating ,sychotic &isorders and &ementia' p. 1>8.


You selected:

A patient with ad!anced6stage Al#heimer%s disease is seen by a physician who prescribes a newer drug that is not a cholinesterase inhibitor. 9his drug is a G6methyl6&6 asparate (GB&A) receptor antagonist. 9his drug is better nown as which of the following? aricept

Incorrect

Correct response:

namenda

Explanation:

4holinesterase inhibitors are not used in late stage Al#heimer%s disease. A newer group of drugs' GB&A receptor antagonists' is a!ailable. Gamenda is thought to wor by decreasing the excitability of neurotransmission caused by an excess of the amino acid glutamate in the 4G. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3H' &rugs 9reating ,sychotic &isorders and &ementia' p. 1C3.


You selected:

Why does phenytoin increase the ris for neonatal hemorrhage in the first 1+ hours after birth? ,henytoin is highly protein bound.

Incorrect

Correct response:

,henytoin is a competiti!e inhibitor of !itamin K.

Explanation:

@ecause phenytoin is a competiti!e inhibitor of !itamin K' it increases the ris for neonatal hemorrhage in the first 1+ hours after birth. 9he ris for neonatal hemorrhage is not increased because phenytoin is highly protein bound' re!ersibly binds to sodium channels while they are in the inacti!e state' and selecti!ely wors at neurons that are firing abnormally. 9he defect is characteri#ed by low le!els of !itamin KFdependent clotting factors' prolonged prothrombin times or partial thromboplastin times' or both. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>&rugs 9reating ei#ure &isorders' p. 722.

A serum carbama#epine le!el of 3+ mcg/m0 is o!er the therapeutic range of + to 31 mcg/m0' necessitating a reduction in dosage. A serum carbama#epine le!el of 8

mcg/m0 is within the th... ( more)


You selected:

A patient has been administered donepe#il 40 for dementia. 9he patient has informed the nurse that she has also been taing nonsteroidal anti6inflammatory drugs. Which of the following interactions should the nurse monitor for in this patient? &ecreased effecti!eness of anticholinergics

Incorrect

Correct response:

ncreased ris of J bleeding

Explanation:

9he interaction of nonsteroidal anti6inflammatory drugs with cholinesterase inhibitors causes increased ris of J bleeding' which should be monitored for. nteraction of anticholi... (more)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3H' &rugs 9reating ,sychotic &isorders and &ementia' p. 1C2.

Jabapentin is frequently used to treat neuropathies. Dnder which of the following conditions should the first dose of the drug be gi!en? n the morning with food

Incorrect


Reference:


At bedtime 9he initial dose of gabapentin should be gi!en at bedtime' because it can cause significant somnolence and di##iness. ( less) Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>- &rugs 9reating ei#ure &isorders' p. 737. Jabapentin is frequently used to treat neuropathies. Dnder which of the following conditions should the

first dose of the drug be gi!en? You selected:

n the morning with food

$ncorrect Correct response: Explanation:

Reference:

At bedtime 9he initial dose of gabapentin should be gi!en at bedtime' because it can cause significant somnolence and di##iness. ( less) Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>- &rugs 9reating ei#ure &isorders' p. 737.

Bethsuximide is administered orally. &ia#epam can be administered rectally. &ia#epam or phenobarbital may be administered intramuscularly. &ia#epam' fosphenytoin' phenytoin' !alproic acid' and phenobarbital can be administered intra!enously. ( less) Question 7: (see full question)

You selected:

While taing the !ital signs of a hospitali#ed client admitted for sei#ure control due to epilepsy' the nurse notices a bloody toothbrush on the clientMs bedside table and scattered bruising o!er the clientMs extremities. What is the nurseMs %est action? &ocument the findings and offer the client a soft6bristled toothbrush.

Incorrect

Correct response:

eport the findings to the primary health care pro!ider immediately.

Explanation:

9he client has a history of epilepsy and is liely taing anticon!ulsants. ematologic changes when taing anticon!ulsants needs to be reported immediately to the health care pro!ider. uch changes include bleeding gums and easy bruising. Abuse is not the liely cause of the clientMs bruising gi!en the history of epilepsy. 9elling the client to as for assistance when ambulating and offering a soft toothbrush are appropriate' but the health care pro!ider needs to be notified immediately about the hematologic changes. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>&rugs 9reating ei#ure &isorders' p. 72+.


You selected:

Which of the following best reflects the action of barbiturates when used to control sei#ures? timulation of the cerebral cortex

Incorrect

Correct response:

nhibition of impulse conduction

Explanation:

@arbiturates inhibit impulse conduction in the ascending reticular acti!ating system. @arbiturates depress the cerebral cortex. @arbiturates depress cerebellar functioning. @arbiturates depress motor ner!e output. (less)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 73+.

While taing the !ital signs of a hospitali#ed client admitted for sei#ure control due to epilepsy' the nurse notices a bloody toothbrush on the clientMs bedside table and scattered bruising o!er the clientMs extremities. What is the nurseMs %est action? &ocument the findings and offer the client a soft6bristled toothbrush.

Incorrect

Correct response:

eport the findings to the primary health care pro!ider immediately.

Explanation:

9he client has a history of epilepsy and is liely taing anticon!ulsants. ematologic changes when taing anticon!ulsants needs to be reported immediately to the health care pro!ider. uch changes include bleeding gums and easy bruising. Abuse is not the liely cause of the clientMs bruising gi!en the history of epilepsy. 9elling the client to as for assistance when ambulating and offering a soft toothbrush are appropriate' but the health care pro!ider needs to be notified immediately about the hematologic changes. (less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>&rugs 9reating ei#ure &isorders' p. 72+.


You selected:

Which of the following best reflects the action of barbiturates when used to control sei#ures? timulation of the cerebral cortex

Incorrect

Correct response:

nhibition of impulse conduction

Explanation:

@arbiturates inhibit impulse conduction in the ascending reticular acti!ating system. @arbiturates depress the cerebral cortex. @arbiturates depress cerebellar functioning. @arbiturates depress motor ner!e output. (less)

Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 73+. Which of the following would the nurse include as possible ad!erse effects when teaching a patient about phenytoin? 0i!er toxicity

Correct

Explanation:

0i!er toxicity is a potential ad!erse effect of phenytoin.

4onstipation' not diarrhea' is an ad!erse effect of phenytion. @one marrow suppression and leuopenia would be ad!erse effects of phenytoin. ,hysical dependence is an ad!erse effect associated with the use of ben#odia#epines. (less) Reference:


You selected:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 722. 9onic6clonic sei#ures and myoclonic sei#ures are classified as what type of sei#ures? (4hoose one) ,artial sei#ures


Jenerali#ed sei#ures

Explanation:

9onic6clonic sei#ures and myoclonic sei#ures are classified generali#ed sei#ures.

Reference:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure

&isorders' p. 1C8. Question 19: !see full "uestion#

You selected:

&ilantin has se!eral side effects. When teaching the patient about these side effects' which symptom would indicate a life6 threatening condition and should be reported to the health care pro!ider immediately? hortness of breath


ash with itching

Explanation:

hortness of breath' alteration in taste' and altered bowel function are all side effects or ad!erse reactions that a patient may experience when taing &ilantin. f the patient has a rash with itching' this could indicate a life6threatening ad!erse reaction such as te!ens6*ohnson syndrome. (less)

Reference:


Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphiaWolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>&rugs 9reating ei#ure &isorders' p. 72H. An >26year6old patient has se!ere pain after a case of shingles. 9he pain is noted along the shoulder and bac. e states the pain is so se!ere he cannot sleep. What is the primary medication that

will relie!e this pain? You selected:

Borphine sulfate (B 4ontin)

Incorrect

Correct response:

Jabapentin (Geurontin)

Explanation:

Jabapentin is the first oral medication appro!ed by the <&A for the management of postherpetic neuralgia. Beperidine will pro!ide pain relief but is not effecti!e in postherpetic neuralgia. Borphine sulfate will pro!ide pain relief but is not effecti!e in postherpetic neuralgia. Gaproxen sodium will decrease inflammation but is not effecti!e for postherpetic neuralgia. ( less)

Reference:

Aschenbrenner' &..'  enable' .*. Drug Therapy in Nursing ' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' p. 737.

After teaching a group of students about anti6sei#ure agents' the Question 4: !see full "uestion# instructor determines that the teaching was successful when the students identify which agent as being administered intra!enously? You selected:

4arbama#epine


Explanation:

Reference:

Aschenbrenner' &..'  enable' .*. &rug 9herapy in Gursing' +th ed.' ,hiladelphia- Wolters Kluwer ealth/0ippincott Williams  Wilins' 1231' 4hapter 3>' &rugs 9reating ei#ure &isorders' pp. 1CC' 728

Jabapentin is frequently used to treat neuropathies. Dnder which of the following conditions should the first dose of the drug be gi!en? You selected:

n the morning with food

Incorrect

Correct response: At bedtime Explanation:

9he initial dose of gabapentin should be gi!en at bedtime' because it can cause significant somnolence and di##iness. ( less)


Which of the following would be most important for the nurse to monitor when administering !alproic acid?

You selected: $ncorrect

4omplete blood count

Answer Key

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