MCQ's in Bone Pathology

MULTIPLE CHOICE QUESTIONS:

1) Osteoid osteoma originates from: a. Periosteum. b. Cortex. c. Medullary caity. d. !ll o" t#e aboe. 2) Sun ray appearance of osteosarcoma is because of: a. Periosteal reactio$. b. Osteo$ecrosis. c. Calci%catio$ alo$& essels. d. No$e o" t#e aboe. 3) Bone metastasis in male commonly arises from cancer of: a. Lu$&. b. Prostate. c. 'id$ey. d. T#yroid. 4) The synonym for Pagets disease is: a. Osteitis %brosa. b. Osteitis (roli"era$s. c. Osteitis de"orma$s. d. No$e o" t#e aboe. !) Osteomalacia predominantly a"ects the: a. S(i$e. b. Pelis. c. S)ull bo$es. d. Metatarsals. #) The en$yme found in osteoclasts but not in osteoblasts is: a. !l)ali$e (#os(#atase. b. !cid (#os(#atase. c. Elastase. d. Cytoc#rome oxidase. %) &'ings tumor a"ecting the humerus a. is a metastasis "rom carci$oma o" t#e t#yroid b. s#ould be treated by immediate am(utatio$ c. loo)s li)e a cut o$io$ o$ x*ray

d. #as a soa(*bubble a((eara$ce o$ x*ray e. dis(lays su$*ray s(icules o$ x*ray

() drenocorticosteroids administered in e*cess cause a. osteo(orosis b. osteosclerosis c. osteoc#o$dritis d. e$doc#o$dral ossi%catio$ e. osteosarcoma +) ,ntestinal absorption of calcium is dependent upon: a. +itami$ , b. Parat#orao$e c. Calcito$i$ d. !ll o" t#e aboe e. No$e o" t#e aboe 1-) Osteoporosis is a de.ciency in: a. Calcium metabolism b. Calcium de(ositio$ c. Protei$ su((orti$& tissue d. !ll o" t#e aboe e. No$e o" t#e aboe 11) Osteomalacia may be due to the follo'ing factors except : a. Staratio$ b. -e(eated (re&$a$cies c. Idio(at#ic steatorr#ea d. I$creased re$al excretio$ o" calcium a$d (#os(#orus e. Prolo$&ed recumbe$cy 12) /enerali$ed osteitis .brosa cystica is characteri$ed by the follo'ing features except: a. ,e%cie$cy o" (arat#ormo$e b. ,iuse decalci%catio$ a$d so"te$i$& o" bo$es c. Cysts co$tai$i$& /r0o$is# 1uid d. Multi(le &ai$t*cell tumors e. Uri$ary sym(toms due to re$al calculi 13) The follo'ing statements about Pagets disease of  bones are true except that it: a. !ects elderly sub2ects3 (articularly males b. Is a &e$erali4ed bo$e dystro(#y o" obscure etiolo&y

c. Causes de"ormities i$ t#e s)ull3 s(i$e3 (elis a$d lo0er limbs d. Produces $o (ressure sym(toms e. Is o"te$ associated 0it# cardioascular com(licatio$s

14) 0hich of the follo'ing statements is untrue in Pagets disease: a. T#e bo$es are &reatly t#ic)e$ed a$d ery ascular b. Cra$ial $ere (alsies may occur c. S(o$ta$eous "ractures are rare d. 5*ray exami$atio$ o" t#e s)ull is dia&$ostic e. Osteo&e$ic sarcoma occurs i$ oer 67 o" cases 1!) 0hich statement is untrue in renal ricets: a. -esults "rom re$al i$su8cie$cy i$ i$"a$cy b. Is due to de%cie$t (#os(#orus3 excretio$ c. Ma$i"ests itsel" by mar)ed d0ar%sm d. Causes $o de"ormities i$ t#e limbs e. E$ds "atally "rom uraemia at (uberty 1#) The most common tumor of the small bones of the hands and feet is: a. E$c#o$droma b. Osteoc#o$droma c. Osteoclastoma d. Ca$cellous osteoma e. /o$e sarcoma 1%) &'ings sarcoma is characteri$ed by the follo'ing except that it: a. Is a commo$ tumor o" c#ildre$ b. !l0ays arises i$ t#e meta(#ysis o" a lo$& bo$e c. Prese$ts as a "usi"orm s0elli$& 0it# i$1ammatory c#a$&es i$ t#e oerlyi$& so"t tissues d. May be associated 0it# leucocytosis e. Produces c#aracteristic radiolo&ical si&$s 1() The most common osteolytic metastases in bones are deried from the: a. Lu$& b. /reast c. Stomac# d. 'id$ey e. Prostate

1+) Ostaomalacia is characteri$ed by the follo'ing features except: a. ,e%cie$t (rotei$ metabolism b. ,emi$erali4atio$ o" t#e bo$es c. Slo0 e(i(#yseal closure d. S)eletal de"ormities e. 5*ray Looser 9s 4o$es  T-UE;!LSE QUESTIONS:

1 ,n Pagets disease of the bone a. t#e serum al)ali$e (#os(#atase is co$siderably raised b. s(iral "ractures o" t#e "emur are commo$ c. dea"$ess is a c#aracteristic o" later sta&es o" t#e diseases d. t#e %bula is ty(ically aected e. osteo&e$ic sarcoma deelo(s t0ice as commo$ly as u$aected (eo(le 2 Pagets disease of bone a. ca$ aect a$y bo$e i$ t#e body b. a((ears (rimarily as a$ osteosclerosis c. causes dea"$ess d. (roduces bo$e t#at is stro$&er t#a$ $ormal bo$e e. aects ca$cellous a$d cortical bo$e 3 Osteomalacia a. is ric)ets i$ t#e adult s)eleto$ b. is due to de%cie$t absor(tio$ o" itami$ ! c. is associated 0it# bli$d loo( sy$drome d. is co$siste$t 0it# a raised serum al)ali$e (#os(#atase e. ca$ be brou&#t about by re$al tubular acidosis 4 The commonest benign tumour of bones is: a. Iory osteoma. b. Ecc#o$droma. c. E$c#o$droma. d.
c. ;ibrosarcoma. d. C#o$drosarcoma. e. Osteosarcoma. ". Lym(#omas o" bo$es.

# ell of origin of osteosarcoma of the bone: a. Osteocytes. b. C#o$drocytes. c. ;ibroblasts. d. Osteoblast. e. Osteoclasts. % Bone site speci.c for osteosarcoma is: a. E(i(#yseal cartila&e. b. E(i(#ysis o" lo$& bo$es. c. ,ia(#ysis o" lo$& bo$e. d. Meta(#ysis o" t#e bo$e. e. No$ o" t#e aboe. ( The common sites of osteosarcoma of bones are: a. Lo0er e$d o" "emur. b. U((er e$d o" tibia. c. S)ull. d. +ertebrae a$d ribs. e. U((er e$d o" #umerus. ". Maxilla. + linical presentations of bone metastases are: a. !$aemia a$d loss o" 0ei&#t. b. /o$e s0elli$&. c. /o$e ac#es. d. Pat#olo&ical "racture. e. Primary cause. 1- The commonest bone to a"ected by pagets disease is: a. Lo$& bo$es es(ecially "emur. b. +ertebrae. c. S)ull. d. ;lat bo$es. e. Sca(ula. 11 The common complications of pagets disease are: a. Mali&$a$t tra$s"ormatio$. b. Heart "ailure. c. Osteoart#ritis.

d. ,islocatio$s. e. Osteoart#ritis.