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Pathway OA
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Pathway OA
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mega_ayu
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UMUR,JENIS KELAMIN,GENETIK,SUKU,KEGEMUKAN, PEKERJAAN
pembentukan tulang baru pada tulang rawan, sendi dan tepi sendi
Kerusakan fokal tulang rawan sendi yang progresif
Perubahan metabolisme tulang
Peningkatan aktivitas enzim yang merusak makro molekul matriks tulang rawan sendi
Penurunan kadar proteoglikan
Berkurangnya kadar proteoglikan
Perubahan sifat - sifat kolagen
Berkurangnya kadar air tulang rawan sendi / cairan sinovial disendi Peradangan di tulang (Osteoarthritis)
Timbul laserasi
Adanya gesekan antar tulang
Mengeluarkan mediator kimia (histamine, bradikinin, prostaglandin) Nyeri bertambah saat men men an kat kat bar baran
Kaku
Penurunan fungsi tulang Melemahnya kekuatan otot
Merangsang reseptor nyeri di medulla spinalis
Gerak menjadi terbatas
Rom terbatas
N eri Merangsang Baroseptor
Intoleransi Aktivitas : Saraf simpatis Peristaltik lambung dan Berkembangnya osteoatritis
Resti cedera
usus
Kerusakan mobilitas fisik
Saraf simpatis Menekan saraf pengendali tidur di hi othalamus
Anoreksia gg. pola tidur
Nodus heberden Kerusakan integritas kulit
Resiko nutrisi kurang dari kebutuhan
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