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Superregulação SIR em resposta a estresse celular Sign upleve to vote on this title SIRT1 regulada ativamente pelo estresse induzido por
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Melhora da função mitocondrial Sign up to vote on this title
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A SIRT1 foi recentemente mostrada com desacetilador e regulador mantendo em níveis b NF-kB (Yeung et al., 2004) TNFα Sign up to vote on this title Useful
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SIRT1 atua na regulação de diversos f transcripcionais. Exemplo: Exemplo: Sign up to vote on this title
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O gene aP2 codifica uma proteína que auxilia o armazenam ar mazenam de gordura Sign up to vote on this title Useful Not useful SIRT1 pode agir como um repressor dogene PPAR, PPAR, assim ate expressão de genes, como o gene de rato aP2 aP 2
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Resultado: Sign up to vote on this title
Mobilização de gorduras
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Estudos genéticos com leveduras, leveduras , mostraram o gene SIR2 estava diretamente relacion Useful
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Uma melhor compreensão do impacto do CR e envelhecimento do sistema nervoso provavelm conduzirá a novas abordagens para a preven Sign up to vote on this title Useful
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MARTIN, Bronwen; MATTSON, Mark P.; MAU up to vote on this title Stuart et al. Caloric restrictionSignand intermittent f Useful Not useful Two potential diets for successful brain aging. Res Rev, Baltimore, p.1-21, 13 jan. 2009.
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